Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.
However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.
New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.
The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.
It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.
"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.
As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.
"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.
"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.
To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.
At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.
Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.
In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.
They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.
Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.
The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.
Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.
Comments
Waoooooo.....
Beef Sukka will be the main menu in this party.
What an idea sirjee, truly a international ___ agenda.
First thing is attending iftar party of haram earning is not permissible to a muslim.... dont host iftar party to show unity in hindu muslims instead go and save the poor hindu muslims who are dying of hunger and non shelter
Indresh Kumar who is the master mind for Samjoutha Express blast and accused in many terror activity in India..! Let them arrange Iftar party at Nagpur head office.
ALLAH is the creator of all that exists and even RSS members comes under it... they are not excluded.
ALLAH will judge according to our deeds done in this life and reward HEAVEN or hell which is eternity.
ALLAH sent many messenger to convey the message of knowing ALLAH who created all that exists & WORSHIP him alone without associating Partners with him.
ALLAH sent QURAN to the last and final messenger and its a guidance to whole of HUMANITY.....not just Muslims.
Quran asks MANKIND to ponder, contemplate and research on what it says. It also asks the intelligent creation of ALLAH to think again & think.
The ONE who is intelligent will understand it better
The ONE who doesnt want to accept - I feel pity on him that he could not recognize his CREATOR.
ALLAH knows What is RSS PLAN here. and ALLAH is the best of PLANNER... Any MUSLIM who attend this iftar party should convey the message of ISLAM. and also mention what happens to human life once ALLAH takes the LIFE back which he has created in the first place.
He can create us once again to give JUSTICE ... its easy for him .
WORSHIP THE CREATOR NOT HIS CREATION
Waoo wonderful Idea what for MRM looks like another part of 72 divisions of the group, any way, things are very/very good Ideology but do not Forget to Invite Our Master NAREN Bai !!!!!!!! you must call him he should have to have see the unity of a group!!!!!!!! no Gangasara served, Naren go buddy enjoy with your friends. Chalo Gujarat, you can see some of the Looted and Burned building.
if this sanghis can serve beef in this event, that will be the great meet i can call.
some negative comments i can c i will challenge those to celebrate diwali and show their real colour, some unwanted group of the country dont want the unity between the two. this is really sad because of few people.
all the best. will pray for the success of this program and this meet should be presented every year.
good move by sangha parivar, lets unite together,
Wow great anyways all the best for this great meet let both the party unite together,
Beef Sukka Serving!!!!
wow good one, everyone can attend?
Sangha Parivar doing good job, lets some dogs bark, nothing can harm the society and true agenda of the sangha parivar. they only want the growth of india. lets support it atleast instead of negative comments.
Please beware this RSS iftar party ...tiz is NAMROOD NARENDRA MODI
Plan...protest tiz type of iftar party....
DRAMA!!!!
or
SHOW OFF
OR
REALITY????
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