22-yr-old woman set afire 42 buses in Bengaluru just for a biryani and Rs 100?

Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.

However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.

New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.

The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.

It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.

"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.

As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.

"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.

"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.

To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.

At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.

Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.

In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.

They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.

Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.

The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.

Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.

Bengaluru, Feb 18: A 26-year-old Kannada singer committed suicide over alleged dowry harassment on Monday. Sushmitha, a playback singer who got married to Sharath Kumar about one-and-a-half years ago, hung herself from the ceiling at her parent's home in Nagarabhavi, Bengaluru on Monday.

The singer sent a Whatsapp to her brother and mother before hanging herself early morning on Monday. She accused her husband and his relatives of dowry harassment in her death note.

According to Bengaluru Police, the singer has accused her husband, his sister and his aunt of harassing her for dowry in her death note. On Monday morning, Sushmitha's brother alerted the police after he found her dead body hanging from the ceiling. She used her dupatta to hang herself.

Sushmitha had lent her voice for Kannada songs in films like Haalu Thuppa and Srisamanya.

Police informed that Sushmitha sent a Whatsapp message to her brother, Sachin, at around 1 am on Sunday and explained that her husband Sharath and her relatives have been harassing her since the time she got married. Sachin read the message at around 5:30am and rushed to her room where he found her hanging from the ceiling.

In the text message, Sushmitha wrote that her husband, Sharath, his sister, Geetha, and his aunt, Vydehi, harassed her and they were the reason behind her ending her life. She also stated that she did not want to end her life in their house and hence came to her parents’ house.

The Annapoorneshwari Nagar police have registered a case of dowry death, charging her husband and his sister and aunt based on complaint filed by Sushmitha’s mother Meenakshi. The three accused are on run after hearing about her death and police said that efforts are on to trace them.

Sushmitha's husband Sharath Kumar is a manager in a car showroom and a resident of KS Nagar in Bengaluru.

Thiruvananthapuram, Apr 24: Kerala Chief Minister Pinarayi Vijayan on Thursday said that there is no community spread or the expected phase three spread of coronavirus in the state so far but the threat continues.

Speaking to media persons here on Thursday, Vijayan said that Kasargod, Kannur, Kozhikode, and Malappuram districts will be in the red zone with full restrictions.

"All the other ten districts in the State will be in the orange zone. With the detection of new cases today, the status of Kottayam and Idukki districts have been changed from green to orange. The district administration will decide on the hotspot areas to be closed," he said.

He said there would be an increase in the number of random tests in the red zones.

"In an effort to confirm that there is no community spread in the State, random antibody tests would be conducted among health workers, police personnel, home delivery persons, volunteers and migrant labourers," he added.

The Chief Minister said that COVID-19 labs set up at the Pariyaram Government Medical College at Kannur and the Kottayam Medical College have got the approval from the ICMR for coronavirus testing. The lab at Kannur Medical College will start functioning from Friday.

The UV sterilised lab, spread over 2,200 sq ft is equipped with four real-time PCR machines. In the first phase, this lab will be able to do 15 tests per day, which will be gradually increased to conduct 60 tests in the next phase.

"With the opening of these two new labs, tests to detect COVID-19 will be conducted in 14 government labs in Kerala. Apart from this, there are two private labs also in Kerala which are doing these tests. Since the number of coronavirus cases is again increasing in the State, the government has decided to procure ten real-time PCR machines to ramp up testing," he added.