Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.
However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.
New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.
The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.
It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.
"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.
As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.
"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.
"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.
To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.
At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.
Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.
In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.
They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.
Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.
The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.
Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.
Comments
Naren
terrorism started from Sikhs not Muslims and till today your people only following it. No need to teach matured person like you so understand the logic of your people.
Is constitution said to make illegal relationship with ladies without marrying them to fulfill your desire? Is your community got the message from constitution to rape in the bus and to kill innocent girl? Constitution made for good will of the citizens not to torture them.
there is no deference between you and Israel but remember we fear Almighty.. Not you or them!
rikacha , nimma root navare kanri , foot alla ... hahaha ...
You cannot expect more than these goondas who dont heistate to worship anything. they don't know what is God
Here we cant show patience or silence.
When justice fails, then Tit for tat is only the ultimate solution.
constitution dont say u can marry 4 , constitution dont say u can do terrorism , killings , rapes , but ur community does it . then whats the problem in telling this ... first of these three rogues are not indians , they look like pakistanis ...isis barodakke they are creating launch pads , but nationalist indians are there to protect hindus , sikhs and christians ..nam deshadalli yaava kumda salafist backed isis nadiyalla ... anybody questions our nations integrity will be strongly dealt with . Muzzies are thinking by doing this they can bring down modi from PM post . no ... not at all possible . there is a deep polarisation even in villages it isnow being felt . by 2024 , India will be hindu rashtra for sure . to amend constitution 2/3 majority needed and all states if we make congress mukht we are done . with coopearting with israelis , defintely we can achieve this . ummah is so weak that it is already divided , no body has guts to speak against India if it does so ... even if they speak , millitarily they are not on par with India .gulf countries want USD from India , for their cheap petrol . hahaha
No one can change the faith by forcing anything.
bitter truth for RSS
Very dangerous for the future of India. Rising intolerance, forcing others what one practices, poking nose in other's matters, dictating what to eat what to wear, all these will eventually lead to sectarian fights, genocides, civil war etc., India may end up in situation similar to Iraq and Iran. BJP sarkar and Sangh parivar must control their bhakts before it is too late.
Constitution even did not say to eat or drink :P
By looking at their face they look very papa, but they raised voice against what other side party asked. strange but true.
What if they call Jai Mata Di or not?
accused must be punished who are they to beat the innocents.
my foot....
Its Their Wish any constitution dint asked all the citizen to call anything particularly.
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