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May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.

According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.

"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.

They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.

Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.

"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.

"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.

In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.

"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.

The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.

These children were then confirmed to have COVID-19.

While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.

Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.

According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.

"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.

Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.

While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.

However, he cautioned that more research is needed to confirm their findings.

"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.

Bantwal, Jun 29: Seven SSLC students, who were on their way to write the examination, were injured in a road mishap near Panemangaluru on Monday.

According to sources, the auto-rickshaw in which the students were travelling overturned causing them injuries.

All the injured were students of Shambur Government high school.

Police said the accident took place as the driver lost control over the vehicle.

Bengaluru, Jul 11: Karnataka on Saturday reported the biggest single-day spurt of 2,798 cases and a record 70 related fatalities, taking the total number of infections in the state to 36,216, the health department said.

The day also saw a record 880 patients getting discharged after recovery.

Out of 2,798 fresh cases, a whopping 1,533 cases were from Bengaluru urban alone.

The previous biggest single-day spike was recorded on July 10 with 2,313 cases.

As of July 11 evening, cumulatively 36,216 COVID-19 cases have been confirmed in the state, which includes 613 deaths and 14,716 discharges, the health department said in its bulletin.

It said out of 20,883 active cases, 20,379 patients are in isolation at designated hospitals and are stable, while 504 are in ICU.

Out of 70 deaths reported, 23 are from Bengaluru urban, 8 from Mysuru, five from Dakshina Kannada, among others.

Most of the dead are either with a history of Severe Acute Respiratory Infection (SARI) or Influenza-like illness (ILI).

Out of 2,798 cases tested positive today, contacts of the majority of the cases are still under tracing.

Among the districts where the new cases were reported, Bengaluru urban accounts for 1533 cases, followed by Dakshina Kannada 186, Udupi 90, Mysuru 83, Tumakuru 78, Dharwad 77 and Yadgir 74.

Bengaluru urban district tops the list of positive cases, with a total of 16,862 infections, followed by DakshinaKannada 2,026 and Kalaburagi 2,024.

A total of 7.99 lakh samples were tested so far, out of which 20,587 were tested on Saturday alone.

So far 7.46 lakh samples have been reported as negative, and out of them 17,488 were reported negative today.