Acclaimed actor Irrfan Khan no more

London/Milan, Jun 2: World Health Organization experts and a range of other scientists said on Monday there was no evidence to support an assertion by a high profile Italian doctor that the coronavirus causing the COVID-19 pandemic has been losing potency.

Professor Alberto Zangrillo, head of intensive care at Italy's San Raffaele Hospital in Lombardy, which bore the brunt of Italy's COVID-19 epidemic, on Sunday told state television that the new coronavirus "clinically no longer exists".

But WHO epidemiologist Maria Van Kerkhove, as well as several other experts on viruses and infectious diseases, said Zangrillo's comments were not supported by scientific evidence.

There is no data to show the new coronavirus is changing significantly, either in its form of transmission or in the severity of the disease it causes, they said.

"In terms of transmissibility, that has not changed, in terms of severity, that has not changed," Van Kerkhove told reporters.

It is not unusual for viruses to mutate and adapt as they spread, and the debate on Monday highlights how scientists are monitoring and tracking the new virus. The COVID-19 pandemic has so far killed more than 370,000 people and infected more than 6 million.

Martin Hibberd, a professor of emerging infectious disease at the London School of Hygiene & Tropical Medicine, said major studies looking at genetic changes in the SARS-CoV-2 virus that causes COVID-19 did not support the idea that it was becoming less potent, or weakening in any way.

"With data from more than 35,000 whole virus genomes, there is currently no evidence that there is any significant difference relating to severity," he said in an emailed comment.

Zangrillo, well known in Italy as the personal doctor of former Prime Minister Silvio Berlusconi, said his comments were backed up by a study conducted by a fellow scientist, Massimo Clementi, which Zangrillo said would be published next week.

Zangrillo told Reuters: "We have never said that the virus has changed, we said that the interaction between the virus and the host has definitely changed."

He said this could be due either to different characteristics of the virus, which he said they had not yet identified, or different characteristics in those infected.

The study by Clementi, who is director of the microbiology and virology laboratory of San Raffaele, compared virus samples from COVID-19 patients at the Milan-based hospital in March with samples from patients with the disease in May.

"The result was unambiguous: an extremely significant difference between the viral load of patients admitted in March compared to" those admitted last month, Zangrillo said.

Oscar MacLean, an expert at the University of Glasgow's Centre for Virus Research, said suggestions that the virus was weakening were "not supported by anything in the scientific literature and also seem fairly implausible on genetic grounds."

Los Angeles, Jan 9: Actors Salma Hayek and Tiffany Haddish are hopeful about the future for women in Hollywood and now cinema is making films about women because the audience was "neglected".

The duo along with Rose Byrne star in Like a Boss, a comedy directed by Miguel Arteta, which follows best friends Mia and Mel (Haddish and Byrne) who join forces to run their own boutique cosmetics company.

When the prospect of a big buyout offer from a notorious titan of the beauty industry (Hayek) tempts them, their lifelong bond - and their business - is put in jeopardy.

Hayek said she is happy with the increase in female-driven films in Hollywood.

"We're on the right path. And we're not going to stop," the actor told Variety.

"What I can tell you is that a lot more women are directing and acting and writing and producing. And there are a lot more movies made about women and for women because the audience was neglected, she said.

She was speaking at the premiere of the film in New York.

Haddish added that the mantle for change shouldn't be left to the traditional decision-makers.

To get things, one has to sometimes make noise, the actor-author said.

"It's about us putting in the work and creating the projects and creating the opportunities in order to do those things to make it better. I sit back and I listen to people talk sometimes, saying, 'They're not letting us; they're not giving it to us.' Why do we have to ask permission? Why can't we just start putting it together? If they want to come on board with it, come on board. And if not, oh well," Haddish said.

"I'm about creating an opportunity. People say I'm loud and obnoxious, but sometimes it’s the squeaky wheel that gets the oil and gets things done," she added.

The comedy comes on the heels of a year gone by in cinema that featured female protagonists in films like Little Women and Captain Marvel.

New Delhi, Jun 15: After Two Indian officials working with Indian High Commission in Pakistan wet missing on Monday,  the Ministry of External Affairs summoned Pakistan's Charge d'affaires to India in the national capital and told them not to interrogate or harass Indian officials.

"Two Indian High Commission officials are missing since morning while on official work. The matter has been taken up with the Pakistani authorities," Akhilesh Singh, First Secretary and spokesperson, Indian High Commission, Pakistan, said.

According to sources quoted by PTI news agency, the MEA told the  Pakistan's Charge d'affaires to India that the responsibility of safety and security of Indian personnel in Islamabad "lays squarely with Pakistani authorities."

"Pakistan was asked to ensure return of two Indian officials along with official car to Indian High Commission in Islamabad immediately," sources added. 

The incident comes after two Pakistani officials at the Pakistani High Commission in New Delhi were accused of espionage and deported.

The two officials have been missing since Monday morning. Officials said the issue has been taken up with the Pakistan government.

Earlier, a vehicle of India's Charge d'affaires Gaurav Ahluwalia was chased by Inter-Services Intelligence (ISI) member.

In March, the Indian High Commission in Pakistan sent a strong protest note to the foreign ministry in Islamabad protesting against the continuing harassment of its officers and staff by Pakistani agencies.