Amit Shah’s plan is to incite communal tension before Karnataka polls: Rao

Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.

However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.

New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.

The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.

It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.

"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.

As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.

"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.

"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.

To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.

At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.

Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.

In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.

They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.

Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.

The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.

Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.

Mangaluru, Jan 24: The third annual nocturnal Mangaluru Kambala, also known as the Rama Lakshmana Kambala, will be held on the night of January 25 at Goldfinch City in Bangra Kuluru, Mangaluru Kambala Samithi president Brijesh Chowta announced on Friday.

The all-night Kambala will have six categories - Naegilu Kiriya, Hagga Kiriya, Naegilu Hiriya, Hagga Hiriya, Kane Halage and Adda Halage.

The event will be inaugurated at 0930 hrs on January 25 and another programme will be held at 1800 hrs.

Benglauru, May 25: Nearly one thousand people in the capital city of Karnataka have lost several crores of rupees to online fraudsters during the two months of covid-19 lockdown.

According to official sources, 962 cases of online frauds have been registered in various police stations across Bengaluru March 23 to May 19. 

On an average, 18 cases were reported every day. However, this number isn’t unusually high compared to normal times, according to police. The highest number of cases was registered in west division (227). 

What baffles the cops is the brazenness with which fraudsters attacked. Many fraudsters duped people in the name of providing jobs, insurance money, Employees’ Provident Fund, renewal of credit/debit cards. 
Many people lost money while procuring groceries, alcohol, masks and hand sanitisers delivered at the doorstep. Olx and Facebook scams thrived during the prolonged lockdown. 

Police said malicious links were shared on mobile phones asking recipients to download the Aarogya Setu app and seeking banking information, all targeted at stealing phone data. 

An officer said many were glued to their phones, and cybercriminals took advantage of this, sometimes pretending to be bank representatives wanting to issue/ renew credit/debit cards.