Anwar murder: BJP calls it political killing; family, cops suspect personal rivalry

Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.

However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.

New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.

The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.

It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.

"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.

As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.

"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.

"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.

To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.

At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.

Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.

In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.

They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.

Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.

The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.

Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.

Bengaluru, Mar 25: Bengaluru Police Commissioner Bhaskar Rao on Wednesday called a meeting of online, e-commerce food, medicine, groceries or animal products delivery aggregators at his office in wake of situation arising out of lockdown imposed in the entire country due to coronavirus epidemic.

The Police Commissioner has appealed one representative from each agency to join him in the meeting at 7 pm.

"I have called a meeting of online, e-commerce food, medicine, groceries, vegetables/fruits or animal products delivery aggregators today at 7 pm at my office at Infantry Road, Bengaluru," said Rao.

"One representative from each agency may please come. We promise all cooperation, please come," he said.
The Indian Council of Medical Research (ICMR) on Wednesday confirmed 539 positive cases of coronavirus in the country.

Prime Minister Narendra Modi had on Tuesday announced a 21-day lockdown in the entire country effective from midnight to deal with the spread of coronavirus, saying that "social distancing" is the only option to deal with the disease, which spreads rapidly.

Bengaluru, Jul 11: Karnataka Animal Husbandry Minister Prabhu Chauhan on Saturday said an ambulance service is being rolled out by the state government in a bid to maintain livestock's health in the state.

"An ambulance service is currently being rolled out by the Department of Animal Husbandry in order to maintain livestock health, livestock farmers in the state," said Prabhu Chauhan.

"A well-equipped ambulance is being provided in 16 districts of the state," he added.

The ambulance that is being introduced has special veterinary facilities including an emergency unit, lab facility, scanning pharmaceutical, and medical equipment, he said.

Chauhan further said that a 'war room' is being prepared to allow veterinarians and livestock farmers to pursue veterinary care in a timely manner.

"For the first time, a 'war room' is being prepared by the Department of Animal Husbandry in Karnataka to allow veterinarians and livestock farmers to pursue veterinary care in a timely manner. The facility will be available 24 hours a day," he added.

Moreover, Karnataka is planning to ban cow slaughter as well by bringing the Prevention of Cow Slaughter and Preservation Bill, 2012.

"Many states have passed the Anti-Cow Slaughter Bill. We are preparing to implement it in Karnataka as well. The state government will soon implement a ban on cow slaughter, sale, and consumption of beef on the lines of many other states," added Chauhan.