Aug 15 target for covid vaccine launch ‘unfeasible’: Indian Academy of Sciences

Thiruvananthapuram, Apr 2: The Centre's decision to accept contributions from abroad to PM-CARES fund for fighting COVID-19 has prompted social media users to take potshots at it as Kerala was not allowed to receive foreign aid after the devastating floods in 2018.

Senior Congress leader Sashi Tharoor said accepting relief for coronavirus pandemic does not affect "one's ego", while other reactions varied from taking a dig saying 'Vikas has reached new heights" to asking where is the country's pride.

Government sources have said a decision had been taken to accept contributions from abroad to the Prime Minister's Citizen Assistance and Relief in Emergency Situations Fund (PM CARES) to deal with the coronavirus pandemic.

The Narendra Modi government had earlier turned away foreign aid, including a reported Rs 700 crore donation from the UAE, to help Kerala during the floods that devastated the southern state, while "deeply appreciating" the offers from various nations then.

Over 480 people were killed, several had gone missing during the worst floods in a century that also rendered lakhs homeless and dealt a severe blow to the state's economy.

"Flood relief for Kerala hurts ones ego. Pandemic relief doesnt. Go figure! #PMCARES!" tweeted Tharoor, who represents Thiruvananthapuram in Lok Sabha.

Another twiterratti reacted to the Centre's latest move, saying: "Wow.. a nation that built 3,000 crore statue is B3GG!NG now? Sad!"

"Vikas has reached new heights... Where are the proud Modi Bhakts?" another wrote.

"Thanks but no, says India to foreign aid for Kerala", another social media user tweeted, tagging a 2018 news report on MEA Spokesperson saying the government was committed to meeting the requirements for relief and rehabilitation in Kerala through domestic efforts.

"Pandemic is unprecedented, India has taken a decision to accept foreign donations to the PM fund. But....", "5 Trillion begging bowl", "Where did the 'National Pride' go now?" another tweet asked.

The Centre's present decision marks a shift from its earlier position of not accepting foreign donations to deal with domestic crisis.

"In view of the interest expressed to contribute to Government's efforts, as well as keeping in mind the unprecedented nature of the pandemic, contributions to the Trust can be done by individuals and organisations, both in India and abroad," a government source has said.

It said the fund was set up following spontaneous requests from India and abroad for making generous contributions to support the government in its fight against COVID-19.

On Saturday, Modi had announced setting up of the PM CARES fund.

New Delhi, May 23: The nationwide lockdown will no longer help India in its fight against COVID-19, and in its place community-driven containment, isolation and quarantine strategies have to be brought into play, leading virologist Shahid Jameel said.

The recipient of Shanti Swarup Bhatnagar Prize for Science and Technology also stressed that testing should be carried out vigorously to identify coronavirus hotspots and isolate those areas.

"Our current testing rate at 1,744 tests per million population is one of the lowest in the world. We should deploy both antibody tests and confirmatory PCR tests. This will tell us about pockets of ongoing infection and past (recovered) infection. This will provide data to open up gradually and let economic activity resume," Jameel told PTI in an interview.

He stressed that testing has to be dynamic to continuously monitor red, orange and green zones and change these based on that data.

About community transmission of COVID-19 in India, Jameel said the country reached that stage long ago.

"We reached community transmission a long time ago. It's just that the health authorities are not admitting it. Even ICMR's own study of SARI (severe acute respiratory illness) showed that about 40 per cent of those who tested positive for SARS-CoV-2 did not have any history of overseas travel or contact to a known case. If this is not community transmission, then what is?" he posed.

Lockdown bought India time in its fight against coronavirus, but continuing it is unlikely to yield any further dividend, Jameel said.

"Instead, community-driven local lockdowns, isolations and quarantines have to come into play. Building trust is most important so that people follow rules. A public health problem cannot be dealt with as a law-and-order problem."

The nationwide lockdown, initially imposed from March 25 to April 14, has been extended thrice and will continue at least till May 31. The virus has claimed 3,720 lives and infected over 1.25 lakh people in the country so far.

Jameel has expertise in the fields of molecular biology, infectious diseases, and biotechnology. He is the CEO of Wellcome Trust/Department of Biotechnology's India Alliance and is best known for extensive research in Hepatitis E virus and HIV.

He said COVID-19 will eventually be controlled through herd immunity, which is acquired in two ways – when a sufficient fraction of the population gets infected and recovers, and with vaccination.

"It is estimated that for SARS-CoV-2 at least 60 per cent of the population would have to be infected and recovered, or vaccinated. This will happen over the course of the next few years," Jameel said.

Herd immunity is reached when the majority of a population becomes immune to an infectious disease, either because they have become infected and recovered, or through vaccination. When that happens, the disease is less likely to spread to people who aren't immune, because there just aren't enough infectious carriers.

"India has 1.38 billion people, a population density of about 400/sq km and a healthcare system ranked at 143 in the world. If we allow 60 per cent people to get infected quickly in the hopes of herd immunity, that would mean 830 million infections," Jameel said.

"If 15 per cent need hospitalization that means about 125 million isolation beds (we have 0.3 million). If five per cent need oxygen and ventilatory support, this amounts to about 42 million oxygen support and ICU beds; we have 0.1 million oxygen support beds and 34,000 ICU beds. This would overwhelm the healthcare system causing mayhem," he said.

Jameel said if the population level mortality is 0.5 per cent that would mean 40 lakh deaths. "Are we prepared to pay this price for herd immunity in the short term? Clearly not," he said.

He said it is unlikely that a vaccine would be available by the end of the year.

"Even then, we don't know yet how long it would give protection – weeks, months, one year, a few years? I don't think we will return to pre-coronavirus days for at least the next 3-5 years. This is also a chance to evaluate if we want to return to those unsustainable, environment-damaging ways. COVID-19 is a timely warning to reform our way of living," he said.

Jameel said it is hard to predict but plausible that COVID-19 would return in second or third wave.

"Later waves come when we don't understand the disease and become lax. A comparison to Spanish Flu is not entirely valid because in 1918 no one knew what caused it. No one had seen a virus till the mid-1930s as the electron microscope needed to view those was invented in 1931," he said.

"Today we know a lot more about the pathogen, its genetic makeup, how it transmits and how to prevent it. We need to be sensible and follow expert advice," he said.

If there is any scientific evidence linking deforestation, rapid urbanisation, climate change with pandemics like COVID-19, he said zoonotic viruses -- those that jump from animals to humans -- happen so when wild animal–human contacts increase.

"Deforestation destroys animal habitats bringing them closer to humans. When you cut forests, bats come to roost on trees closer to human habitations. Their viruses in secretions/stool get transmitted to domestic animals and on to humans. This happened clearly with Nipah virus outbreak in Malaysia in 1997-98 from fruit bats to pigs to humans," he said.

"COVID-19 possibly arose in wet animal markets due to dietary habits that bring all kinds of live and dead wild animals in close contact with humans," Jameel added.

New Delhi, Apr 28: Nafisa Ali took to Instagram to share the inspiring story of her niece, Diya Naidu, who donated her plasma to help patients suffering from Covid-19 after recovering from the disease. The veteran actress shared a photo of her niece from the hospital bed and asked fans to read Diya's post to get a detailed account of her experience.

Nafisa wrote, "Diya Naidu my niece - a COVID19 hero - is back home after donating her plasma - looks like liquid gold - it’s value is priceless as it will save lives. So please read her COVID19 story and share the information that is first hand. It is the need of the hour. Help save lives. #diyanise. #diyanaidu #covid_19 #india (sic)."

Diya Naidu, who is a dancer and choreographer based in Bengaluru, revealed in her Instagram post that she has donated her plasma for other Covid-19 patients. She said that the method has been super effective wherever it's been tried.

Earlier, Nafisa Ali gave a shout-out to her niece on Instagram and penned a heartfelt note for her. She wrote, "I am so grateful to you brave child - a COVID19 warrior (living in Bangalore) has agreed to donate her plasma to help cure other COVID19 serious patients (sic)."

Explaining the process of plasma therapy to treat Covid-19 patients, she wrote, "The process of donating plasma to treat COVID-19 is not very complex and can be done in just two hours. One of the most discussed methods of treatment of the disease caused by the novel coronavirus is plasma therapy, which involves the transfusion of plasma from a convalescent coronavirus patient to a critical patient. The blood of a recovering patient is rich in antibodies produced by the body to fight the virus, which are expected to help the critical patient recover (sic)."

Plasma therapy has been suggested to treat people suffering from Covid-19. People, who have recovered from the disease, are donating plasma as it contains antibodies to fight the disease. Earlier, Kanika Kapoor, who was the first Bollywood celebrity to be diagnosed with the disease, also offered to donate her plasma. She has recovered from Covid-19 and is currently living with her family in Lucknow.