Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.
However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.
New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.
The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.
It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.
"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.
As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.
"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.
"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.
To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.
At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.
Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.
In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.
They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.
Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.
The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.
Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.
Comments
Modi govt has failed miserably in protecting minorities rights in the country..
Yours is one of the worst sites I have come across - disabling both Control+v and Control+c etc. Shame on you.
There is a Karnataka Prevention of Cow Slaughter and Cattle Preservation Act, 1964 in force in Karnataka, Section 4 of which lays down: \4. Prohibition of Slaughter of Cow or Calf of She-buffalo:- Not withstanding any law, usage or custom to the contrary, no person shall slaughter or cause to be slaughtered, or offer or cause to be offered for slaughter or otherwise intentionally kill or offer or cause to be offered for killing any cow or calf of she-buffalo.\" The law is framed by Congress government four decades back and is very much in force. As such, what the dalits did was illegal - a crime - for which they are liable to 6 months imprisonment or fine or both. Well, that does not give license to vigilantes of any party or organization to take law into their own hands and beat them up either. The only course was to stop the killing if possible, or seize the slaughtered cow (carcass) etc. and hand over to the police. If the police do not act, then they could agitate in public, etc. So both parties are wrong on this occasion."
NRI PM S ACCHE DIN FOR INDIANS
The day Mr. Narendra Modi became prime minister , all such goondasm raised in our country. Narendra Modi can't talk because these are the part of his mentor (RSS) programmes.
These goons (Bhajrangis) are paid goons of BJP.
Time has come for Daliths and Minorities to stand against these criminals.
This is Karnataka not Gujurat. Strict punishment should be handed out to the perpetrators of such a heinous crime. As per the Constitution people are free to eat what they please. Why should the Bajrang Dal or anyone get offended if anybody eats beef.
BD will get their reward from the devils who inspire them to do such acts... Devils are permanent residence in HELL... it is easy for them to take human to HELL when people encourage EvIL in the society... Evil in the society spreads when People dont Ponder or want to know about the CREATOR of all that exists...
ISLAM says no one will escape of their crime, A day will be there to JUDGE all that happened in this EARTH. and JUSTICE will be done by the CREATOR who created U me and all that exists.
Add new comment