May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
Comments
Bajrang Dal still exist in Mangalore because majority of followers are monkeys. They just goes with stupid and illiterate people without questioning their background. Most of Bajrang Dal leader either ex-ladies bar owner or conductors.(uneducated or criminals).
Monkey Dal gathered together to discuss their own created issues. They have nothing to discuss other than children's plays.
It's funny how these activists say a lie so many times and make it appear like the truth..I'm ashamed to call them hindus..because I have amazing Hindu friends (whom I believe are true hindus). Love jihad? What rubbish!this shows how much you cook up stories. Dont waste money on unnecessary programmes. Donate it to poors..so many are in need of money. Btw don't think muslim men are jobless. there are enough pious muslim girls in our country whom they can get married to. We are not in shortage.
Also need a discussion regarding hiring muslims in all job sectors across karnataka
Tigale gant marilu....bhoomig bhara
Mangalore was peaceful for quite sometime.....now again goons became jobless I hope.... smart city ... developments all gaya bhaad me...
Gaaf me dhum hai to try to stop your girls or punish them...your.people will throw you in garbage.....try that way.....
Discuss right now LOVE JIHAD founder is sitting in front of you (CHOTE MIA)I dont remember his name sitting on your extreme left. Why to spend Money start now itself.
Fake People.
I could not understand why these waste and burden to earth... hate mongers are talking on love jihad time and again whereas such issue does not exist in reality, but exists only in the mind and agenda of sangh parivar. This is to fool people and gain political benefit. Love Jihad is not a concept in any religion, particularly in Muslims and this is a fake + man made concept by sangh parivar. We, the peace loving people of karnataka should oppose and raise against these hate mongers.
After a long period of rest, culprits are back to trouble. Peace loving Mangalorean be careful and be happy with your family.
Indians in india cant eat beef but indian beef can be eaten in other parts of the world....what a joke....
Bajrangies go and stop exporting if you have got ba**s....
Jihad means a spiritual struggle within oneself against Sin.
Prophet Muhammad pbuh. taught us...
Alcohol destroys U and your family life
Gambling destroys U and your family life
Interest destroys U and your family (It may give a temporary enjoyment of the money lend to U by banks but in long term when U see most of the people have become BANKRUPT...
(Look Mallya - Whatever he owns did not benefit him...one day U will c the real color).
Quran says Trade is acceptable but not Riba (Interest).
True Muslims strive hard NOT TO involve in such evils of the society & They strive to stay away from these sins and also other such things in life...
God promises to give more when we follow his commandments ... it is not just for muslims but it should be recognized by the whole of mankind..
Most of the People are just listening to the ISLAM-HATERS and judging without verifying. But the CREATOR of all that exists asks us to use our INTELLECT and Verify before You come to any conclusion of any matter in your LIFE... if not YOU will be regretting later...
Love Jihad is fake and a creation of cheddi and its allies..who wants to spread corruption in the society.
Wonderful decision by wonderful lads of Bajji and Ranjjis, what you mean of \Cow Trafficking\" at present I am in HONG KONG really fantastic INDIAN BEEF Avails here, no problem at all, so these wonderful Tidy Bear??? Master Hamarappa Puranik only Barking, If he IS having GuTs, Strength let him ask Indian Prime minister Modianna, to Cancel Exporting Licence that is the Gentleman's work Keeping some Chelas around catching Labour, Driver, Butcher, Cleaner like humans.. they are catching and punishing that's women's work Annanna, come front line and catch real culprits.
NAREAN Bai where are you Sir?? Are you Near by !!!!! Keep it up Baisabb."
1) U have forgotten most important issue..... ban exporting of beef and find out how many of your goons are into this business....
2) At the right age with out if girls are married off, issues of love marriage maybe solved
3) drugs ok.....go ahead, nice step
For such matters press meet is not necessary, can be discussed within yourself
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