May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
Comments
Masha Allah
Majority of Indian population are dalit, If 70% of dalits convert to Islam in India.Islam will become the number one in India.
Any individuals while choosing religion, he will go for the best religion.
Finally he will find Islam, because Islam is the best and easy to follow religion.
Accepting any religion means, agreeing its doctrine and following its teaching.
It has come to from the heart. Nobody can force to follow any religion nor can force to change it.
It comes from his inner conscience, what he or she feels comfortable.
We may force somebody to remain in the same religion or we can force also to change into any religion, which is like asking someone to agree and believe 2+2=3. Even if a person agrees to come under pressure, it means, he is not following its teaching by will and wish. So he can definitely violate and disobey its teaching.
Now coming into this case, first of all they are not comfortable what their fellow followers did them to ban the entry into temple. And no equality in their society. This is the main reason
Now choosing new religion is purely understanding and convincing its doctrine and real teaching.
Our constitution also empowers everyone to follow freely any religion. Not only this, it also empowers to propagate to others.
It is a great constitution.
Guide them properly OR Leave them alone.
Accepting any religion means, agreeing its doctrine and following its teaching.
It has come to from the heart. Nobody can force to follow any religion nor can force to change it.
It comes from his inner conscience, what he or she feels comfortable.
We may force somebody to remain in the same religion or we can force also to change into any religion, which is like asking someone to agree and believe 2+2=3. Even if a person agrees to come under pressure, it means, he is not following its teaching by will and wish. So he can definitely violate and disobey its teaching.
Now coming into this case, first of all they are not comfortable what their fellow followers did them to ban the entry into temple. And no equality in their society. This is the main reason
Now choosing new religion is purely understanding and convincing its doctrine and real teaching.
Our constitution also empowers everyone to follow freely any religion. Not only this, it also empowers to propagate to others.
It is a great constitution.
Guide them properly OR Leave them alone.
Welcome brothers and sisters ....Proud to be MUSLIMS
Islam invites people who learn about it and understand it. not to increase numbers....no need to convert just because they are not allowed in temples, they can follow their faith even from their hearts.
@ venki
Islam does not allow forced conversion.....we invite to the path of Islam. If someone wills then only..moreover we are not minorities in the world like you.....
@yogesh..
i think the people already know better to join islam than supporting RSS Terrorrists right....
Hari, nothing is impossible in this world, for that you need good heart and mind which I cannot see it in those so called hindutva group....they are all still remaining in their old and orthodox thinking. As a matter of fact there is no such a thing called upper and lower cast in the society but it has been created by bloody brahmins for their benefits...
Venke, Sangeeth .....if you feel that one can pray at home, then why you people are fighting for Ayodhya temple.... Beef exporting hypocrites....
If they convert to Islam....there they get all types of respect, which they have not seen and imagined in their entire past life...great religion......nice choice....well come guys....
Sangeeth Manglore
Yeah... they can pray anywhere as they are considered born out of feet.. Only those born out of Gods head, needed rich temples to pray and enjoy public wealth. Opportunistic
Hindutva group will do nothing if Dalits convert to Jainism, Buddhism but, as soon as Dalits want to convert to Islam or Christianity, Saffronist will come into action with some stupid solution
The best solution is as mention by Mr Rikaz, that all the Dalits must get BRAHMIN STATUS then all the discrimination may end.
Good that hindutava group is taking initiative......they should upgrade their status from lower caste (dalit) to upper caste (Brahmin) This is only the amicable solution for this problem, otherwise this problem (ill treating dalit) will recur every now and then.
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