Bantwal: Vigilantes attack two men for transporting cattle

May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.

According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.

"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.

They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.

Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.

"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.

"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.

In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.

"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.

The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.

These children were then confirmed to have COVID-19.

While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.

Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.

According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.

"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.

Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.

While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.

However, he cautioned that more research is needed to confirm their findings.

"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.

Bengaluru, Jan 25: The Karnataka government would hold a Global Investors' Meet (GIM 2020) in Bengaluru from November 3-5 to showcase the southern state's ecosystem for attracting investments from the world over, an official said on Friday.

"Our Chief Minister B.S. Yediyurappa held the first road show on the GIM at the 50th World Economic Forum (WEF) annual meeting, being held at Davos in Switzerland and invited global firms to participate in the 3-day event for investment opportunities," additional secretary P. Ravikumar told IANS.

At a curtain-raiser on "Invest Karnataka 2020" on Thursday, the BJP Chief Minister said the theme of the GIM would be "Innovate Now. Growth Forever" as the state had one of the best natural and human resources for investing in manufacturing, services and agriculture sectors and creating jobs.

"About 100 entrepreneurs, businessmen and heads of global firms participated in the roadshow to assess the state's industrial policies, incentives, infrastructure, tax system and its ease of doing business for investment potential," Ravikumar said.

Among the participants at the event were Swiss-India parliamentary group president Niklaus-Samuel Gugger, Uber Chief Executive Dara Khosrowshahi, General Electric (GE) executive William Cowan and heads of Gemini Corporation, Coca Cola, SAP Labs, Swiss Re and Mitsubishi Heavy Industries.

"Khosrowshahi discussed Uber's expansion plans in Bengaluru and assured the Chief Minister of investing more in the state. Cowen expressed interest in the development of healthcare, renewable energy and power distribution across the state through partnership with the state government," the official noted.

The US-based transnational firm (GE) has a large presence in Bengaluru with one its largest engineering and technology centres and two production plants.

"A Coca Cola executive told Yediyurappa that the soft beverage firm would initially invest $25 million in its plants in the state and enhance it to $200 million to benefit farmers and rural people with access to clean drinking water in their villages," Ravikumar said.

The Chief Minister also sought to know the investment or expansion plans of global firms present in the state, especially Bengaluru and assured their heads of the state support in creating hundreds of jobs and wealth.

About 100 members of the Indian delegation to the WEF, led by Union Commerce and Industries Minister Piyush Goyal, Confederation of Indian Industry (CII) director-general Chandrajit Bannerjee, Bharat Forge chairman Baba Kalyani, Kirloskar Systems Managing Director Vikram Kirloskar, also participated in the state's GIM roadshow.

State Industries Minister Jagdish Shettar, chief secretary T. M. Vijaya Bhaskar, additional chief secretary E.V. Ramana Reddy and industrial department principal secretary Gurav Gupta also attended the state event.

"Emiriti Lulu Group chairman M.A. Yusuf Ali discussed plans to invest $300 million (Rs 2,160 crore) in logistics, hospitality and health/wellness sectors across the state with Yediyurappa," said Ravikumar.

Ali, an NRI (non-resident Indian) migrated to the United Arab Emirates (UAE) from Kerala two decades ago and founded the Lulu Group at Abu Dhabi to operate a chain of hypermarkets and retail firms since 2000.

"The Chief Minister assured Ali of speedy approvals and incentives for investing in the state, with ease of doing business," the official said in an e-mail to IANS from the Swiss town.

Asserting that his proactive government would work overtime to facilitate global investments in the southern state, Yediyurappa said he was committed to create more jobs across sectors.

Dassault Systems executive Florene Verzelen told the chief minister about her company's plans to set up centres of excellence in smart manufacturing and smart cities in the southern state.

"The centres will train and equip the youth with skilled jobs in large corporations the world over," Ravikumar reiterated.

Yediyurappa apprised US aerospace behemoth Lockheed Martin executive Richard Ambrose of the ecosystem for aerospace and defence industry in the state, especially Bengaluru.

"I will soon visit Bengaluru to explore the possibilities of investing more in Karnataka and taking up research and development work," said Ambrose on the occasion.

A delegation from global automotive component maker Denso also called on the chief minister and interacted with the state delegation.

The Japanese firm has an excellence and research centre in New Delhi and a manufacturing unit at Nelamangala on the outskirts of Bengaluru.

Denso executive Hiroyuki Wakabasyi said he would visit Bengaluru soon to explore further investments in the state.

"Arcelor Mittal chairman Laxmi Mittal also met the chief minister and discussed his company's investment plans in the state," the official added.

Mittal backed out of setting up a steel plant in the state's northern region over a decade ago due to delays in acquiring land and mandatory approvals.

Drug maker Novo Nordisk chief executive Lars Fruergaard expressed readiness to work with the state government in taking up educative and awareness programmes for diabetic patients.

Mangaluru, Jan 14: Mangaluru city police commissionerate his notified traffic diversions on NH 73 in view of massive protest at Adyra Kannur in the city against CAA, NPR and NRC on January 15. It also has issued guidelines for the public, protesters and organisers of the protest.