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Beauty products can be reason for pregnancy complications

Agencies
January 21, 2018

New Delhi, Jan 21: 'Cosmetics enhance beauty' is the reason for us to use them. But, we hardly think that they can affect us more than we realize.

Mounting research on this subject has raised certain concerns regarding the potential side effects of these products. The chemicals present in the cosmetics and beauty products have shown various complications and side effects on the hormonal, as well as the reproductive system of women.

Environmental chemicals and their effects on reproductive function have become a hot topic in the field of reproductive medicine. Most of the cosmetics including nail polish, anti-bacterial soaps, anti-aging creams, hair sprays and perfumes have a severe effect on female fertility due to the toxic chemicals present in it.

"In the recent years, several endocrine disrupting chemicals have been identified to affect abnormal ovarian function, miscarriages and female infertility. Soaps, the supreme germ killer, but antibacterial soap can also kill your chances of conceiving. Antibacterial soaps, contains chemical triclosan which is linked to endocrine disruption that mess up with your hormones and interfere with the reproductive system. Parabens are a type of preservative (soaps, shampoos and conditioner) used to prevent the growth of bacteria. But too much of it can have impact on fertility. When hormones are out of balance, the chances of creating healthy eggs or healthy sperm is reduced." says Dr Nitasha Gupta, Gynaecologist and IVF Specialist, Indira IVF Hospital, New Delhi.

With the presence of many volatile organic compounds, formaldehyde, Phthalate like dibutyl Phthalate (DPT) and toluene as ingredients in nail polish, these chemicals pose a high risk to cause fertility issues, misconception and even birth defects. Women who polish their nails very frequently are at a greater concern in terms of facing fertility issues. Phthalates are known to cause infertility in both the males and females. It is sometimes advised for the people working in beauty salons for hours to take precautionary measures.

"Polish removers contain toxic chemicals too including acetone, methyl methacrylate, toluene, and ethyl acetate. The most commonly used chemical is a solvent named toluene which is often used in cosmetics for getting glossy finish. This chemical is known to affect the central Nervous System (CNS) and harm to the reproductive system. Another such chemical which is more profound in beauty products are the phthalates, which are also a reason for disrupting the hormone levels, impairs fertility and aids in building up of breast milk during pregnancy. A chemical found in nail polish - TPHP (Triphenyl phosphate) is immediately metabolized to DPHP (diphenyl phosphate) and can put women at an elevated risk of fertility problems." said Dr Alka, Udaipur based IVF expert.

Exposure to these chemicals puts you at a higher risk of miscarrying and the baby at risk for physical and mental birth defects. The defects may include preterm birth, increased chances of miscarriage, learning problems and cognitive impairment, behavioural issues and even damage to the kidney, brain and the nervous system.

"So, we need to give a thought about the safety of the products before we use them. Excess use of cosmetics can be disastrous to pregnancy and the chances of conceiving may reduce drastically owing to their serious effects on reproductive environment. Though IVF treatments help in conceiving, avoiding use of such chemicals is advisable, as even after conception, continued excess usage can cause miscarriage and birth defects," added Dr Gupta.

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Agencies
January 25,2020

Washington D.C., Jan 25: A new study conducted by a team of researchers reveals why individuals who have a history of early life adversity (ELA) are disproportionately prone to opioid addiction.

The study conducted examined how early adversities interact with factors such as increased access to opioids to directly influence brain development and function, causing a higher potential for opioid addiction.

The study was lead by UCI researchers and was published in Molecular Psychiatry.

Tallie Z. Baram, MD, PhD, the Danette Shepard Chair in Neurological Sciences at the UCI School of Medicine and one of the senior researchers for the study, was on the take that the widely known factor genetics that plays major role in addiction vulnerability, cannot be solely held responsible for the recent rise in opioid abuse.

To further clarify, the researchers simulated ELA in rats by limiting bedding and nesting materials during a short, postnatal period of time.

In female rats, this led to striking opioid addiction-like characteristics including an increased relapse- behaviour, for example.

As observed in addicted humans, the rats were willing to work very hard (pay a very high price) to obtain the drug.

Baram said: "Ultimately, we found that conditions during sensitive developmental periods can lead to vulnerability to the addictive effects of opioid drugs, especially in females, which is consistent with the prevalence of ELA in heroin-addicted women."

These findings can be used to highlight the importance given to sex differences in future ELA-related studies on opioid addiction, and in future prevention or intervention strategies being developed to address the growing opioid crisis.

The study conducted examined how early adversities interact with factors such as increased access to opioids to directly influence brain development and function, causing a higher potential for opioid addiction.

The study was lead by UCI researchers and was published in Molecular Psychiatry.

The study found that unpredictable, fragmented early life environments may lead to abnormal maturation of certain brain circuits, which profoundly impacts brain function and persists into adolescence and adulthood.

Tallie Z. Baram, MD, PhD, the Danette Shepard Chair in Neurological Sciences at the UCI School of Medicine and one of the senior researchers for the study, was on the take that the widely known factor genetics that plays major role in addiction vulnerability, cannot be solely held responsible for the recent rise in opioid abuse.

To further clarify, the researchers implanted ELA in rats by limiting bedding and nesting materials during a short, postnatal period of time.

In female rats, this led to striking opioid addiction-like characteristics including an increased relapse- behaviour, for example.

As observed in addicted humans, the rats were willing to work very hard (pay a very high price) to obtain the drug.

Baram said: "Ultimately, we found that conditions during sensitive developmental periods can lead to vulnerability to the addictive effects of opioid drugs, especially in females, which is consistent with the prevalence of ELA in heroin-addicted women."

These findings can be used to highlight the importance given to sex differences in future ELA-related studies on opioid addiction, and in future prevention or intervention strategies being developed to address the growing opioid crisis.

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Agencies
June 23,2020

The record levels of new daily COVID-19 cases are due to the fact that the pandemic is peaking in a number of big countries at the same time and reflect a change in the virus' global activity, the World Health Organisation said.

At a media briefing on Monday, WHO's emergencies chief Dr Michael Ryan said that the numbers are increasing because the epidemic is developing in a number of populous countries at the same time.

Some countries have attributed their increased caseload to more testing, including India and the US But Ryan dismissed that explanation.

We do not believe this is a testing phenomenon, he said, noting that numerous countries have also noted marked increases in hospital admissions and deaths neither of which cannot be explained by increased testing.

There definitely is a shift in that the virus is now very well established, Ryan said. The epidemic is now peaking or moving towards a peak in a number of large countries.

He added the situation was definitely accelerating in a number of countries, including the US and others in South Asia, the Middle East and Africa.

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