Beef terror: Tense situation in Dadri as hate-mongers gear up for violence

Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.

However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.

New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.

The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.

It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.

"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.

As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.

"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.

"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.

To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.

At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.

Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.

In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.

They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.

Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.

The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.

Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.

Mangaluru, Mar 4: Fifteen Iranian fishermen, arrested for illegally entering Indian waters, were shifted from Mangaluru to Central Prison Bengaluru at Parappana Agrahara recently.

 On October 21, coast guard officials intercepted two fishing vessels near Gayathri island, about 168 nautical miles off Mangaluru Coast and took into custody 15 crew members after they failed to produce necessary documents.

While one of the boats capsized after developing a technical snag, the other boat was brought to Mangalore Port.

On the basis of a written complaint lodged by Indian Coast Guard (ICG) Deputy Commandant Kuldeep Sharma, Karnataka State Coastal Security Police (KSCP) station in Mangaluru filed case against the 15 Iranian fishermen under Maritime Zone of Indian Act 1981.

Mangaluru, Feb 5: The New Mangalore Port implemented the Centre's Standard Operating Procedure (SOP) by screening the crew of cargo ships and passengers of Cruise Vessel for the highly contagious and deadly disease Coronavirus.

Sources in the port said that screening was being carried out at the harbour since the past few days, as a precautionary measure. All the 1,800 passengers and 786 crew of Cruise Vessel 'Costa Victoria,' which stopped at the port, were screened.

Arrangements were also made for screening foreign nationals arriving at the Mangalore International Airport (MIA). 

Besides screening, passengers were also made aware of the Coronavirus and the precautionary steps to be taken.