Beware: Your food might contain these toxins

Agencies
June 2, 2017

New Delhi, Jun 2: Ever thought you would be consuming heavy metals or cigarette butts with your food? As a rule of thumb, foods are generally safe. However, there are things that get into food, which could shock and disgust you enough to keep away from food altogether.toxins

What will surprise you further is that many of these things are permitted by the food safety authorities, but within limits. Some substances, like certain toxins, are naturally present in foods. And so, even if the food authorities wanted, they could not ban them totally.

Some of these ‘foreign’ substances might not be dangerous, but not even in your wildest imagination could you have thought that they could be on your plate, says Dr Saurabh Arora, founder, Food Safety Helpline.com.

1. Snack with maggots.

Next time you eat a burger or open sealed packs of foods, or cans of mushrooms and tomatoes, check carefully. It could be infested with maggots and insect eggs. Your cabbage and spinach could have caterpillar larvae in it. Believe it or not, a limited number of maggots are permitted in food, says Dr Arora.

2. Ever wondered what rats do in your food?

Rodents scavenge for food and rummage in food stocks. In fact, rodents could make stored foods their home if entry is not strictly prevented. Where there is laxity, rodent hair, urine and droppings enter foods and from there to your plate. So watch out as your food could be biologically contaminated.

3. They live in drains, dustbins and in your food.

Cockroaches, flies, insects of all kinds, and even spiders, and lizards can fall into food and are regarded as being highly dangerous if found in foods as they can carry bacteria from dustbins and drains to foods. The presence of rodents and insects is a food safety violation that could result in cancellation of license for food establishments.

4. What are cleaning agents doing in your food?

Cleaning agents like ammonia, bleach, dishwashing liquids and sanitizers can cause turmoil. People have had them with their coffee because the personnel forgot to rinse out the coffee machine thoroughly. Human error it could be but the carelessness in not rinsing and washing utensils or cooking surfaces thoroughly can lead to not only a bad taste but some stomach burning and even food poisoning. Cleaning agents need to be stored away from all food preparation areas and utensils. Cooking and food preparation surface areas must be cleaned, washed and sanitised only when food preparation is over and no food is outside. Such carelessness ruins reputations of food establishments.

5. Unseen dangers have roots.

Moulds and fungus grow on foods when the temperature is warm. The rainy season finds these in abundance in sauces, jams, jellies, cooked and processed meats and poultry, cheese, bread and even fruit. Surface moulds can be washed or dusted off but that does not mean they have gone away completely. The fungus has roots that go deep into foods and these are not visible to the naked eye. Dishcloths, towels, sponges and mops, if not kept clean, spread moulds which land up in your food. Avoid anything smelling musty and stale, and check vegetable and fruit stems to detect moulds.

6. Are you sure your milk products have no melamine?

Are you sure that the infant formula you are feeding your child with, or the chocolate and frozen yogurt you are eating is free of melamine? Melamine is synthetic material used to make plastic tableware and dishware, adhesives and even whiteboards. So what’s it doing in your food? Water is often mixed into milk and such milk loses proteins. So to enhance the content of protein, melamine is mixed in it. Products made from milk could have melamine which can damage the kidneys permanently.

7. Packaging infuses chemicals into food.

Antimony and tin are used in packaging materials from where they can enter food. Foils, cans, pans and storage containers have chemicals which can be released from them into food at low levels. When ingested, they cause various health problems.

8. You could be ingesting heavy metals.

Copper, brass, cadmium, lead, zinc, mercury and even arsenic could be in your food. Metals leach into foods from the environment and from utensils used for cooking and serving food. Cracked or chipped pewter dishes, pottery dishes with glazed lead, or those pretty enamelled dishes you cook and serve food in can leave lead or cadmium in your foods and can even react with acidic foods like tomatoes, orange juice and pickles. Copper cooking utensils, buckets and tubs made from galvanised metals like zinc, and plumbing pipes also introduce metals into foods. Mercury and arsenic can reach foods through water and cadmium and lead from soil. All these heavy metals can cause toxicity when ingested and could even damage the liver, kidneys, central nervous system and blood, while mercury can cause sensory, visual and auditory problems also. Since chemicals cannot be seen, adequate and regular food testing is required to ensure that foods are free from these elements at all points in the food chain.

9. Tea with a taste of iron.

Iron filings can enter tea when it is processed as particles escape into tea from the wear and tear of iron machinery. Iron remains in the body and though some iron is good for the body, it could become dangerous and lead to heart problems if you are a tea addict and drink copious amounts of it. The permissible limit for iron filings in tea in India is presently 150 mg per kilogram of tea.

10. Human beings leave their own stamp on foods.

While human hair found in food might not be as hazardous as animal hair, but their presence in food indicates that the establishment lacks in good hygienic practices. Besides hair; nails, false nails, nail polish, pieces of jewellery, paper napkins and even cigarette butts can enter food and have been found, more often than anyone would like to admit. All personnel working in the food service industry need to be made aware of these hazards and instructed and trained to follow good hygiene practices.

11. Mice and horse in your processed meat.

Animal hair or chipped pieces of bone can be naturally present in meat food products. Perhaps what you may not be aware of is that whole mice can sometimes be churned into foods during processing. Unscrupulous manufacturers add horse and even rat meat to canned meat food products to cut costs, especially those imported, as some countries permit horse meat.

12. Extraneous materials that can break your teeth.

They say sticks and stones won’t break bones but stones in food might break your pearly whites. You must have seen dirt, mud, manure, leaves, twigs and other filth and even insect excreta in some raw grains and other agricultural products. While some of these can be removed by picking them out, what about insect excreta? When raw materials are processed into cereals and bakery products, do these remain or have they been cleaned before processing?

13. What’s cooking, metal or glass?

Metal fragments from worn or chipped equipment and containers enter food products during processing. However, glass, plastic and metal pieces from glass tumblers, edges of badly opened tin cans, and carelessly opened caps on foods, and even shattered light bulbs fall into food without anyone realising it. Wood pieces from wooden surfaces or chopping boards slip into food too. Even a small piece of any of these substances can cause major problems if swallowed. Most establishments use shatterproof bulbs and open tin cans and bottles away from foods being cooked.

14. Sand and sawdust special.

Have you felt that grit on your tongue? It could be sand in your salt, soup and coffee whitener. Sand is mixed in powdered foods as sand absorbs moisture and prevents clumping. Sawdust is used for the same reason in foods like shredded cheese. It also makes low-fat ice cream creamy and ready-to-drink milkshakes smooth.

15. Are these food additives really permitted?

The fruit juice you enjoy so much could have sulphites. Sulphites are deliberately added to fruit juices, in some soft drinks, instant tea vinegar and wine to keep them tasting fresh. While preservatives and flavour enhancers improve the looks and taste of foods yet some of them could cause allergic reactions.

16. Of hormones and antibiotics.

Livestock are given antibiotics and growth hormones in their feeds so they can remain healthy and grow bigger quickly. If you are a non-vegetarian, you could find these growth hormones and antibiotics in the animal meats which you eat. Eating animal meats that contain antibiotic makes you resistant to them.

17. From plants to your plate.

Residues of pesticides, herbicides and chemical fertilizers used during the agricultural process easily find their way into food. Pesticides may leave residues on the skins and surface of fruits and vegetables. Residues of pesticides and herbicides, over a period of time, can affect the central nervous system, respiratory and gastrointestinal system.

18. Gelatine: veg or non-veg?

Some vegetarian foods like certain cereals could contain animal gelatine which is used as a binding agent so that the sugar sticks to the cereal. Read the labels minutely if you are a vegetarian or you could find you’ve just eaten animal bone and skin as some gelatine are made from these.

19. Carcinogens in your foods.

Bright coloured foods look attractive but the truth is that synthetic dyes like Red 3 and Citrus Red 2, Blue 1, Blue 2, Green 3, Red 40 and Yellow 6 are carcinogenic and could cause various kinds of cancer and allergic reactions too.

20. What does your chewing gum contain?

If you are one of those who loves to pop a chewing gum into your mouth, then you could actually be eating a secretion from sheep wool called Lanolin. This additive is used in chewing gum because it has an oily texture which makes it easy to chew that gum.

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Agencies
June 17,2020

Leading physicians are celebrating a small dose of good news that arrived Tuesday about dexamethasone, a cheap and widely used steroid shown to be able to save lives among COVID-19 patients, but also cautioning against releasing study results by press release during a global health emergency, like in the case of the latest dexamethasone study by University of Oxford.

"It will be great news if dexamethasone, a cheap steroid, really does cut deaths by one-third in ventilated patients with COVID19, but after all the retractions and walk backs, it is unacceptable to tout study results by press release without releasing the paper", Atul Gawande, surgeon and CEO of Haven Healthcare, tweeted.

"Bottom line is, good news," Dr. Fauci, America's foremost infectious diseases expert told a US newswire on Tuesday, soon after the dexamethasone results were announced in the UK.

Fauci, who has long championed the therapeutics-first view said that dexamethasone is a "significant improvement" in the available therapeutic options currently available.

On Medical Twitter and Facebook, doctors broadly agree that dexamethasone use aligns well with the way COVID19 attacks the body's immune system. Fauci said the results in the Oxford study make "perfect sense" in that context.

"We should see the number of people who actually survive go up, if the study holds up," virologist and epidemiologist Dr. Joseph Fair told a television network.

Global coronavirus cases crossed 8 million on Tuesday. In the US, Texas and Florida are facing a new wave of cases after lifting lockdown orders earlier than medical experts recommended. Amidst the relentless graph upwards, the dexamethasone study results injected hope for better survival rates among those most seriously ill.

World Health Organization chief scientist Soumya Swaminathan welcomed the results from the randomised control trial.

Dr Eugene Gu, Founder and CEO of CoolQuit tweeted that he is "genuinely impressed" with the UK dexamethasone trial. This may be a "game changer", he wrote.

"There's no conflict of interest as dexamethasone is a generic steroid. The mechanism of action makes sense because steroids can reduce cytokine storms and overactive immune systems that makes COVID-19 so deadly. The number needed to treat is 8 ventilated patients which is great."

The Oxford study found that dexamethasone reduced deaths by 35 percent in patients who needed treatment with breathing machines and by 20 percent in those only needing supplemental oxygen. Dexamethasone was one of 5 drugs studied in a large clinical trial in the United Kingdom named RECOVERY, short for Randomised Evaluation of COVID-19 Therapy.

Peter Horby, chief investigator of the University of Oxford clinical trial, said dexamethasone is the first drug to be shown to improve survival in COVID-19. Details of the study have not been released. The trial organisers said they made their announcement via a news release because of "the public health importance of these results." According to Horby's public comments, there was a lot of initial resistance to studying steroids.

During the study, 2,104 patients were randomly selected to be given 6 milligrams of dexamethasone once a day (either by mouth or by intravenous injection) for 10 days. That group was compared with 4,321 patients who received the usual care alone.

Researchers estimated that dexamethasone would prevent one death for every eight patients treated while on ventilators and one for every 25 patients on extra oxygen alone.

UK experts have called the study results a breakthrough in the fight against the virus. The researchers have promised they would publish the results soon.

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Agencies
May 26,2020

Tedros Adhanom Ghebreyesus, the World Health Organisation's (WHO) Director-General, said that a clinical trial of hydroxychloroquine (HCQ) on COVID-19 patients has come to "a temporary pause", while the safety data of the the anti-malaria drug was being reviewed.

According to the WHO chief, The Lancet medical journal on May 22 had published an observational study on HCQ and chloroquine and its effects on COVID-19 patients that have been hospitalized, reports Xinhua news agency.

The authors of the study reported that among patients receiving the drug, when used alone or with a macrolide, they estimated a higher mortality rate.

"The Executive Group of the Solidarity Trial, representing 10 of the participating countries, met on Saturday (May 23) and has agreed to review a comprehensive analysis and critical appraisal of all evidence available globally," Tedros said in a virtual press conference on Monday.

The review will consider data collected so far in the Solidarity Trial and in particular robust randomized available data, to adequately evaluate the potential benefits and harms from this drug, he said.

"The Executive Group has implemented a temporary pause of the HCQ arm within the Solidarity Trial while the safety data is reviewed by the Data Safety Monitoring Board. The other arms of the trial are continuing," Tedros added.

WHO initiated the Solidarity Trial, a plan to evaluate the safety and efficacy of four drugs and drug combinations against COVID-19 more than two months ago, which include HCQ.

According to the WHO, over 400 hospitals in 35 countries are actively recruiting patients and nearly 3,500 patients have been enrolled from 17 countries under the Solidarity Trial.

Tedros added that the safety concern over the drug related only to the use of HCQ and chloroquine in COVID-19, and "these drugs are accepted as generally safe for use in patients with autoimmune diseases or malaria".

"WHO will provide further updates as we know more," he added.

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Agencies
June 22,2020

A team of scientists has produced first open source all-atom models of full-length COVID-19 Spike protein that facilitates viral entry into host cells – a discovery that can facilitate a faster vaccine and antiviral drug development.

The group from Seoul National University in South Korea, University of Cambridge in the UK and Lehigh University in the US produced the first open-source all-atom models of a full-length S protein.

The researchers say this is of particular importance because the S protein plays a central role in viral entry into cells, making it a main target for vaccine and antiviral drug development.

"Our models are the first full-length SARS-CoV-2 spike (S) protein models that are available to other scientists," said Wonpil Im, a professor in Lehigh University.

"Our team spent days and nights to build these models very carefully from the known cryo-EM structure portions. Modeling was very challenging because there were many regions where simple modeling failed to provide high-quality models," he wrote in a paper published in The Journal of Physical Chemistry B.

Scientists can use the models to conduct innovative and novel simulation research for the prevention and treatment of Covid-19.

Though the coronavirus uses many different proteins to replicate and invade cells, the Spike protein is the major surface protein that it uses to bind to a receptor.

The total number of global COVID-19 cases was nearing 9 million, while the deaths have increased to over 467,000, according to the Johns Hopkins University.

With 2,279,306 cases and 119,967 deaths, the US continues with the world's highest number of COVID-19 infections and fatalities, according to the CSSE.

Brazil comes in the second place with 1,083,341 infections and 50,591 deaths.

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