Bypolls to 3 assembly constituencies in Karnataka on February 13

Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.

However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.

New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.

The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.

It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.

"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.

As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.

"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.

"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.

To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.

At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.

Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.

In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.

They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.

Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.

The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.

Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.

Mangaluru, Feb 1: “1) Take necessary precautionary measures. 2) Don’t blindly believe in social media rumours.” These are the two important advisories issued by the authorities in Dakshina Kannada district in the wake of coronavirus scare.

According to DHO Dr Ramakrishna there is no specific antiviral treatment recommended for coronavirus infection. Supportive care for infected people can be highly effective, but, there is no vaccine available for coronavirus.

In a health meeting, he advised people to take precautionary measures to prevent the spread of the virus. Following are some of the precautionary measures.

1) Wash your hands often with soap and water or an alcohol-based sanitiser.

2) Avoid touching your eyes, nose and mouth with unwashed hands.

3) Avoid close contact with people who are sick.

4) Stay home when you are sick, and cover your mouth when you cough or use a tissue while sneezing.

5) Throw the used tissue in the dustbin. Clean and disinfect surfaces frequently.

Deputy commissioner Sindhu B Rupesh said there is no need for people to panic about coronavirus.

Dakshina Kannada zilla panchayat CEO R Selvamani said IEC programmes will be held to create awareness on possibilities of spread of diseases.

He also advised people not to follow blindly the advisories being shared on social media, especially WhatsApp without proper verification.

“Posts on cures for coronavirus which are not scientifically proven are being shared on social media. Do not follow such advisories without verifying facts,” he said.

Mangaluru, July 13: With the confirmation of four more deaths related to novel coronavirus, the covid-19 death toll in Dakshina Kannada has mounted to 50.

In fact, the four fatalities had occurred on Saturday. Today the authorities concerned that they were tested positive for Covid-19.

The deceased include two septuagenarians, a sexagenarian, and a 53-year-old. All of them were male.

Dakshina Kannada deputy commissioner Sindhu B Rupesh revealed that their comorbidities were diabetes in ICU, pneumonia in ICU, hepatitis in ICU, severe acute  respiratory infection and carcinoma of the lung respectively.