Childhood bullying may up heart disease, diabetes risk

March 12, 2017

Washington, Mar 12: Children who are bullied may experience lifelong health effects related to chronic stress exposure such as increased risk for heart disease and diabetes in adulthood, new research has found.bullying

Recent advances in understanding of the negative health effects of chronic stress highlight a pressing need to clarify the longer-term health implications of childhood bullying, researchers said.

"Bullying, as a form of chronic social stress, may have significant health consequences if not addressed early," said Susannah J Tye, from the Mayo Clinic in the US.

"We encourage child health professionals to assess both the mental and physical health effects of bullying," said Tye.

"Bullying has been linked to an increased risk of psychiatric disorders, although there are still questions about the direction of that association," researchers said.

Bullied children also have increased rates of various physical symptoms - recurrent and unexplained symptoms may be a warning sign of bullying.

"It is important that we appreciate the biological processes linking these psychological and physiological phenomena, including their potential to impact long-term health," Tye said.

Studies of chronic stress exposure raise concerns that bullying may have lasting effects on physical health.

Any form of continued physical or mental stress can put a strain on the body, leading to increasing "wear and tear."

This process, called allostatic load, reflects the cumulative impact of biological responses to ongoing or repeated stress—for example, the "fight or flight" response.

"When an individual is exposed to brief periods of stress, the body can often effectively cope with the challenge and recover back to baseline," Tye said.

"Yet, with chronic stress, this recovery process may not have ample opportunity to occur, and allostatic load can build to a point of overload," she said.

"In such states of allostatic overload, physiological processes critical to health and well-being can be negatively impacted," she added.

With increasing allostatic load, chronic stress can lead to changes in inflammatory, hormonal, and metabolic responses.

Over time, these physiological alterations can contribute to the development of diseases - including depression, diabetes, and heart disease - as well as progression of psychiatric disorders.

Early-life stress exposure can also affect the way in which these physiological systems respond to future stressors.

This may occur in part through epigenetic changes—alterations in gene function related to environmental exposures—that alter the stress response itself.

Chronic stress may also impair the child's ability to develop psychological skills that foster resilience, reducing their capacity to cope with future stress.
The research appears in the journal Harvard Review of Psychiatry.

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Agencies
January 5,2020

Washington D.C., Jan 5: After a woman filed a lawsuit against a diet soda company, the California court has declared that the beverage does not promise to help buyers in losing weight.

The woman had gulped down the drink for over a decade but did not lose inches as a result.

The three-judge panel declared during the hearing: "The prevalent understanding of the term in (the marketplace) is that the 'diet' version of a soft drink has fewer calories than its 'regular' counterpart."

However, the members of the US 9th circuit court have felt that the consumers tend to make out something of their own that is unreasonable and eventually hamper the reputation of brands through a deceptive allegation, reports Fox News.

The response was due to a misleading case filed against Diet Dr Pepper by Shana Becerra from Santa Rosa, California. Shana claimed that she has been addictively purchasing the low-calorie beverage for the past 13 years hoping for losing some fat but failed to lose even a single inch.

The woman also stated that the attractive and fit models misled her into believing that drink will help her in perfecting her body like them.

However, the court's decision was that advertisements are for representational purposes only. "Cannot be reasonably understood to convey any specific meaning at all," as written by Judge Jay Bybee.

Shana had last week made such allegation against Diet coke as well where the court came to a similar verdict. She claimed that she had found various studies where it is evident that the artificial sweetener aspartame used in diet beverages actually boosts weight gain.

But the artificial sweetener is approved in by the concerned administrative department and thus is used in most American drinks.

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Agencies
March 27,2020

New Delhi, Mar 27: The Centre has restricted sale and distribution of "hydroxychloroquine" declaring it as an essential drug to treat the COVID-19 patients and meet the requirements of emergency arising due to the pandemic.

The Ministry of Health and Family Welfare on Thursday made the announcement making it clear that the order "shall come into force on the date of its publication in the official Gazette".

In the order, the government declared that the Central government is "satisfied that the drug hydroxychloroquine is essential to meet the requirements of emergency arising due to pandemic COVID-19 and in the public interest, it is necessary and expedient to regulate and restrict the sale and distribution of the drug 'hydroxychloroquine' and preparation based thereon for preventing their misuse".

"Now, therefore, in exercise of the powers conferred by Section 26B of the Drugs and Cosmetics Act, 1940 (23 of 1940), the Central government hereby directs that sale by retail of any preparation containing the drug Hydroxychloroquine shall be in accordance with the conditions for sale of drugs specified in Schedule H1 to the Drugs and Cosmetics Rules, 1945."

The order came at a time when the novel coronavirus claimed 16 lives and infected over 600 people across India.

The announcement regarding ban of sale and distribution of the drug was made by the government earlier but it issued an official Gazette notification on Thursday signalling that hydroxychloroquine -- an anti-Malaria drug -- will work as a medicine for treating coronavirus infected patients as well.

Recently, the national task force for COVID-19 constituted by Indian Council for Medical Research (ICMR) has recommended hydroxy-chloroquine as a preventive medication.

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Agencies
May 26,2020

Tedros Adhanom Ghebreyesus, the World Health Organisation's (WHO) Director-General, said that a clinical trial of hydroxychloroquine (HCQ) on COVID-19 patients has come to "a temporary pause", while the safety data of the the anti-malaria drug was being reviewed.

According to the WHO chief, The Lancet medical journal on May 22 had published an observational study on HCQ and chloroquine and its effects on COVID-19 patients that have been hospitalized, reports Xinhua news agency.

The authors of the study reported that among patients receiving the drug, when used alone or with a macrolide, they estimated a higher mortality rate.

"The Executive Group of the Solidarity Trial, representing 10 of the participating countries, met on Saturday (May 23) and has agreed to review a comprehensive analysis and critical appraisal of all evidence available globally," Tedros said in a virtual press conference on Monday.

The review will consider data collected so far in the Solidarity Trial and in particular robust randomized available data, to adequately evaluate the potential benefits and harms from this drug, he said.

"The Executive Group has implemented a temporary pause of the HCQ arm within the Solidarity Trial while the safety data is reviewed by the Data Safety Monitoring Board. The other arms of the trial are continuing," Tedros added.

WHO initiated the Solidarity Trial, a plan to evaluate the safety and efficacy of four drugs and drug combinations against COVID-19 more than two months ago, which include HCQ.

According to the WHO, over 400 hospitals in 35 countries are actively recruiting patients and nearly 3,500 patients have been enrolled from 17 countries under the Solidarity Trial.

Tedros added that the safety concern over the drug related only to the use of HCQ and chloroquine in COVID-19, and "these drugs are accepted as generally safe for use in patients with autoimmune diseases or malaria".

"WHO will provide further updates as we know more," he added.

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