Clinton, Trump sprint to finish in final campaign appeals

November 8, 2016

Philadelphia, Nov 8: Closing out a wildly unpredictable White House race, Hillary Clinton and Donald Trump blitzed through battleground states Monday in a final bid to energize supporters. Clinton, backed by an emotional appeal from Barack Obama, urged voters to embrace a "hopeful, inclusive, bighearted America," while Trump vowed to "beat the corrupt system."

ClintonThe candidates rallied voters late into the night, a frenzied end to a bitter election year that has laid bare the nation's deep economic and cultural divides. Clinton and Trump were both nostalgic at times, looking back fondly at a campaign that has put each on the brink of the presidency.

Clinton campaigned with confidence, buoyed by FBI Director James Comey's announcement Sunday that he would not recommend criminal charges against her following a new email review. The FBI inquiry had sapped a surging Clinton momentum at a crucial moment in the race, though she still heads into Election Day with multiple paths to the 270 Electoral College votes needed to become the nation's first female president.

Clinton closed her campaign alongside the last two Democrats to occupy the Oval Office, Obama and her husband, former President Bill Clinton, as well as first lady Michelle Obama. In a nod to the deep divisions that await the next president, Clinton said she'd come to "regret deeply how angry the tone of the campaign became." She cast the choice facing voters Tuesday as a "test of our time."

"We know enough about my opponent, we know who he is," Clinton said, addressing tens of thousands of people sprawled across Philadelphia's Independence Mall. "The real question for us is what kind of country we want to be."

Obama's address amounted to a valedictory for a president whose popularity has grown in his final year in office.

"America, I'm betting on you one more time," Obama said. "I am betting that tomorrow you will reject fear and choose hope."

Trump, who sped through five rallies Monday, recalled the rivals he'd vanquished and how far he's come since launching his improbable candidacy. As he surveyed the crowd in Scranton, Pennsylvania, he declared, "It's been a long journey."

Still, Trump was aggressive to the end, slamming Clinton as the "face of failure." Having made the new FBI review a centerpiece of his closing case to voters, he argued that the Democrat was being protected by a "totally rigged system."

"You have one magnificent chance to beat the corrupt system and deliver justice," Trump said. "Do not let this opportunity slip away."

The comments were a reminder that Comey's news, delivered in a letter to lawmakers on Sunday, was a doubled-edged sword for Clinton. While it vindicated her claims that the emails would not yield new evidence, it ensured that a controversy that has dogged her campaign from the start would follow her through Election Day.

Across the country, nearly 24 million early ballots were cast under the shadow of Comey's initial announcement of a new email review. That number represents about half of the nearly 45 million people who had cast votes by Monday, according to Associated Press data.

The inquiry involved material found on a computer belonging to Anthony Weiner, the disgraced former congressman and estranged husband of Huma Abedin, a longtime Clinton aide. Comey said Sunday the FBI reviewed communications "to or from Hillary Clinton while she was secretary of state."

Clinton tried to fly above the controversy Monday, making no mention of the FBI during her rallies. She was closing out her campaigning with a midnight rally in Raleigh, North Carolina.

Clinton is banking in part on high turnout — particularly among Obama's young, diverse coalition of voters — to carry her over the finish line Tuesday. Roughly half the states with advance voting have reported record turnout, including Florida and Nevada, which have booming Hispanic populations, a possible good sign for Clinton.

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News Network
April 10,2020

Melbourne, Apr 10: Scientists have identified six drug candidates from more than 10,000 compounds that may help treat COVID-19.

The research, published in the journal Nature, tested the efficacy of approved drugs, drug candidates in clinical trials and other compounds.

"Currently there are no targeted therapeutics or effective treatment options for COVID-19," said Professor Luke Guddat from the University of Queensland in Australia.

"In order to rapidly discover lead compounds for clinical use, we initiated a programme of high-throughput drug screening, both in laboratories and also using the latest computer software to predict how different drugs bind to the virus," Guddat said.

The project targeted the main COVID-19 virus enzyme, known as the main protease or Mpro, which plays a pivotal role in mediating viral replication, the researchers said.

This makes it an attractive drug target for this virus, and as people don't naturally have this enzyme, compounds that target it are likely to have low toxicity, they said.

"We add the drugs directly to the enzyme or to cell cultures growing the virus and assess how much of each compound is required to stop the enzyme from working or to kill the virus. If the amount is small, then we have a promising compound for further studies," said Guddat.

After assaying thousands of drugs, researchers found of the six that appear to be effective in inhibiting the enzyme, one is of particular interest.

"We're particularly looking at several leads that have been subjected to clinical trials including for the prevention and treatment of various disorders such as cardiovascular diseases, arthritis, stroke, atherosclerosis and cancer," Guddat said.

Researchers said compounds that are already along the pipeline to drug discovery are preferred, as they can be further tested as antivirals at an accelerated rate compared to new drug leads that would have to go through this process from scratch.

"With continued and up-scaled efforts we are optimistic that new candidates can enter the COVID-19 drug discovery pipeline in the near future," Guddat said.

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News Network
July 10,2020

Lahore, Jul 10: The Punjab government enforced smart lockdown in seven cities of the province for 15 days with an immediate effect from Thursday night, The News International reported.

The Primary and Secondary Healthcare Department on Thursday issued a notification under the Punjab Infectious Diseases Ordinance 2020, about enforcement of lockdown in Lahore, Multan, Faisalabad, Gujranwala, Sialkot, Gujrat and Rawalpindi, till July 24 midnight.

In Lahore, the lockdown will be enforced in A2 Block Township, EME Society, Main Bazaar Chungi Amr Sadhu, Punjab Government Servants Housing Scheme, Wapda Town, C-Block Jauhar Town and Green City.

The basic necessities of life will remain available in smart lockdown areas. "The purpose of the smart lockdown is to minimise movement of people in hotspots of positive coronavirus cases," said Capt (retd) Muhammad Usman, Secretary, Primary and Secondary Healthcare Department.

The country registered 2,751 new COVID-19 cases during the last 24 hours, taking the tally to 243,599 on Friday. The province-wise breakup includes 85,261 cases in Punjab, 100,900 cases in Sindh, 29,406 in Khyber Pakhtunkhwa, 11,099 in Balochistan, 13,829 in Islamabad, 1,619 in Gilgit-Baltistan and 1,485 in Pakistan-occupied Kashmir.

The death toll due to the virus reached 5,058 with 75 more deaths reported over the last 24 hours, as per data cited by Radio Pakistan.

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July 1,2020

Jul 1: Hong Kong police moved swiftly on Wednesday against protesters gearing up for the first rally since the introduction of sweeping security legislation, making their first arrest under it and warning of punishment for pro-independence material.

Beijing on Tuesday unveiled the details of the much-anticipated law after weeks of uncertainty, pushing China's freest city and one of the world's most glittering financial hubs onto a more authoritarian path.

As hundreds of protesters gathered downtown for an annual rally marking the 23rd anniversary of the former British colony's handover to China, riot police used pepper spray to arrest at least two people, while one metro station closed.

Police, who earlier banned the rally, cited the law for the first time in confronting protesters and they also made their first arrest under it - a man holding a flag advocating independence.

"You are displaying flags or banners/chanting slogans/or conducting yourselves with an intent such as secession or subversion, which may constitute offences under the ... national security law," police said in a message displayed on a purple banner.

The law will punish crimes of secession, subversion, terrorism and collusion with foreign forces with up to life in prison, heralding a more authoritarian era for the Asian financial hub.

China's parliament adopted it in response to months of pro-democracy protests last year triggered by fears that Beijing was stifling the city's freedoms, guaranteed by a "one country, two systems" formula agreed when it returned to Chinese rule.

Authorities in Beijing and Hong Kong have repeatedly said the legislation is aimed at a few "troublemakers" and will not affect rights and freedoms, nor investor interests.

But critics fear it will crush the freedoms that are seen as key to Hong Kong's success as a financial centre.

"With the release of the full detail of the law, it should be clear to those in any doubt that this is not the Hong Kong they grew up in," said Hasnain Malik, head of equity research, Tellimer in Dubai.

"The difference is that U.S. and China relations are far worse and this could be used as a pretext to impede the role of Hong Kong as a finance hub."

In Beijing, Zhang Xiaoming, executive deputy director of Beijing's Hong Kong and Macau Affairs Office, told reporters suspects arrested by Beijing's new security office in Hong Kong could be tried on the mainland.

He said the mainland's national security office abided by Chinese law and that Hong Kong's legal system could not be expected to implement the laws of the mainland. Article 55 of the law states that Beijing's national security office in Hong Kong could exercise jurisdiction over "complex" or "serious" cases.

Mainland security agencies will also be based in Hong Kong officially for the first time, with powers that go beyond city laws.

"The law is a birthday gift to (Hong Kong) and will show its precious value in the future," Zhang said, adding the law would not be applied retroactively.

On July 1 last year, hundreds of protesters stormed and vandalised the city's legislature to protest against a now-scrapped bill that would have allowed extraditions to mainland China.

Those protests evolved into calls for greater democracy, paralysing parts of the city and paving the way for Beijing's imposition of the law this week.

'INEVITABLE'

Speaking at a flag-raising ceremony to mark the handover anniversary, the city's Beijing-backed leader, Carrie Lam, said the law was the most important development since the city's return to Chinese rule.

"It is also an inevitable and prompt decision to restore stability," Lam said at the same harbour-front venue where 23 years ago the last colonial governor, Chris Patten, a staunch critic of the security law, tearfully handed back Hong Kong to Chinese rule.

Some pro-Beijing officials and political commentators say the law is aimed at sealing Hong Kong's "second return" to the motherland after the first failed to bring residents to heel.

Luo Huining, the head of Beijing's top representative office in Hong Kong, said at the ceremony the law was a "common aspiration" of Hong Kong citizens.

Critics denounced the lack of transparency surrounding the details of the legislation until it was unveiled. It came into force at 11 p.m. (1500 GMT) on Tuesday.

Some pro-democracy activists gave up membership of their groups just before the law came into force, though calling for the campaign for democracy to go on offshore.

"I saw this morning there are celebrations for Hong Kong's handover, but to me it is a funeral, a funeral for 'one country two systems'," said democracy lawmaker Kwok Ka-ki.

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