Co-sleeping mothers at higher risk of developing depression, new study claims

Agencies
March 2, 2018

Washington, Mar 2: Turns out, mothers who co-sleep with infants beyond six months may feel more depressed and judged by others.

According to a Penn State-study, mothers who choose to co-sleep with their infants are more likely to feel depressed or judged when faced with recent trends and popular advice telling moms not to sleep with their babies.

After analyzing moms' sleeping patterns and feelings about sleep for the first year of their babies' lives, the researchers found that mothers who were still co-sleeping - sharing either a room or bed - with their infants after six months were more likely to feel depressed, worried about their babies' sleep and think their decisions were being criticized.

Douglas Teti of the Penn State said that regardless of current parenting trends, it's important to find a sleep arrangement that works for everyone in the family.

"In other parts of the world, co-sleeping is considered normal, while here in the U.S., it tends to be frowned upon," Teti said. "Co-sleeping, as long as it is done safely, is fine as long as both parents are on board with it. If it's working for everyone, and everyone is okay with it, then co-sleeping is a perfectly acceptable option."

The researchers said that while most American families begin co-sleeping when their babies are first born, most of those families transition the babies to their own room by the time he or she is six months old. Teti said concerns about sudden infant death syndrome (SIDS) or the desire for babies to learn how to fall asleep on their own may be why many parents in the U.S. prefer their babies to be sleep alone.

Teti said this study - which analysed the sleeping habits of 103 mothers in their baby's first year of life - saw a similar pattern in its participants. "We found that about 73 percent of families co-slept at the one-month point. That dropped to about 50 percent by three months, and by six months, it was down to about 25 percent," Teti said. "Most babies that were in co-sleeping arrangements in the beginning were moved out into solitary sleep by six months."

On average, mothers that were still co-sleeping after six months reported feeling about 76 percent more depressed than mothers who had moved their baby into a separate room. They also reportedly felt about 16 percent more criticised or judged for their sleep habits.

"We definitely saw that the persistent co-sleepers -- the moms that were still co-sleeping after six months -- were the ones who seemed to get the most criticism," Teti said. "Additionally, they also reported greater levels of worry about their baby's sleep, which makes sense when you're getting criticized about something that people are saying you shouldn't be doing, that raises self-doubt. That's not good for anyone."

Teti said that the study isn't about whether co-sleeping is good or bad, but about the importance of finding a sleep arrangement that works well while not neglecting your partner or spouse.

"If you're going to co-sleep, you have to make sure both people in the partnership have talked it through and both people are in sync with what they want to do," Teti said. "If not, that's when criticism and arguments can happen and possibly spill over into the relationship with child. So you want to avoid that. You need to make sure you have time with your partner, as well."

Teti also said that even when co-sleeping works well, it can still cause more loss of sleep for the parents than if the baby slept in its own room.

"If you co-sleep, it is going to disrupt your sleep, and probably Mom's sleep more than Dad's," Teti said. "So this is something to be careful with if you're not good with chronic sleep debt. Co-sleeping needs to work well for everyone, and that includes getting adequate sleep. To be the best parent you can be, you have to take care of yourself, and your child benefits as a result", concluded Teti.

The study is published in the journal Infant and Child Development.

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Agencies
June 10,2020

Early treatment with the antiviral drug remdesivir has been found to reduce viral load and prevent lung disease in macaques infected with SARS-CoV-2 that causes COVID-19, according to a study.

The findings, published in the journal Nature on Tuesday, support the early use of remdesivir treatment in patients with COVID-19 to prevent progression to pneumonia.

Researchers from the National Institutes of Health in the US noted that remdesivir has broad antiviral activity and has been shown to be effective against infections with SARS-CoV and MERS-CoV in animal models.

The drug is being tested in human clinical trials for the treatment of COVID-19, they said.

Researcher Emmie de Wit and colleagues investigated the effects of remdesivir treatment in rhesus macaques, a recently established model of SARS-CoV-2 infection.

Two sets of six macaques were inoculated with SARS-CoV-2.

One group was treated with remdesivir 12 hours later -- close to the peak of virus reproduction in the lungs -- and these macaques received treatment every 24 hours until six days after inoculation.

In contrast to the control group, the researchers found that macaques that received remdesivir did not show signs of respiratory disease, and had reduced damage to the lungs.

Viral loads in the lower respiratory tract were also reduced in the treated animals; viral levels were around 100 times lower in the lower-respiratory tract of remdesivir-treated macaques 12 hours after the first dose, they said.

The researchers said that infectious virus could no longer be detected in the treatment group three days after initial infection, but was still detectable in four out of six control animals.

Despite this virus reduction in the lower respiratory tract, no reduction in virus shedding was observed, which indicates that clinical improvement may not equate to a lack of infectiousness, they said.

Dosing of remdesivir in the rhesus macaques is equivalent to that used in humans, the researchers noted.

They cautioned that it is difficult to directly translate the timing of treatment used in corresponding disease stages in humans, because rhesus macaques normally develop only mild disease.

However, researchers said the results indicate that remdesivir treatment of COVID-19 should be initiated as early as possible to achieve the maximum treatment effect.

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Agencies
January 11,2020

Europe, Jan 11: Researchers have revealed the people who drink tea at least three times a week have healthy years of life and longer life expectancy.

The research was published in the European Journal of Preventive Cardiology, a journal of the European Society of Cardiology (ESC).

Dr Xinyan Wang, who is the author of the study, said: "Habitual tea consumption is associated with lower risks of cardiovascular disease and all-cause death. The favourable health effects are the most robust for green tea and for long-term habitual tea drinkers."
The analysis that was conducted included about 100,902 participants of the China-PAR project2 with no history of heart attack, stroke, or cancer.

Participants were classified into two groups: Habitual tea drinkers and never or non-habitual tea drinkers and followed-up for a median of 7.3 years.

The analyses estimated that 50-year-old habitual tea drinkers would develop coronary heart disease and stroke 1.41 years later and live 1.26 years longer than those who never or seldom drank tea. Compared with never or non-habitual tea drinkers, the habitual tea consumers had a 20 per cent lower risk of incident heart disease and stroke, 22 per cent lower risk of fatal heart disease and stroke, and 15 per cent decreased risk of all-cause death.

The potential influence of changes in tea drinking behaviour was suspected in a subset of 14,081 participants with assessments at two-time points. The average duration between the two surveys was 8.2 years, and the median follow-up after the second survey was 5.3 years.

Habitual tea drinkers who maintained their habit in both surveys had a 39 per cent lower risk of incident heart disease and stroke, 56 per cent lower risk of fatal heart disease and stroke, and 29 per cent decreased risk of all-cause death compared to consistent never or non-habitual tea drinkers.

Senior author Dr Dongfeng Gu said: "The protective effects of tea were most pronounced among the consistent habitual tea drinking group. Mechanism studies have suggested that the main bioactive compounds in tea, namely polyphenols, are not stored in the body long-term. Thus, frequent tea intake over an extended period may be necessary for the cardioprotective effect."

In a subanalysis by type of tea, drinking green tea was linked with approximately 25 per cent lower risks for incident heart disease and stroke, fatal heart disease and stroke, and all-cause death. However, no significant associations were observed for black tea.
Dr Gu noted that a preference for green tea is unique to East Asia.

Two factors may be at play. First, green tea is a rich source of polyphenols which protect against cardiovascular disease and its risk factors including high blood pressure and dyslipidaemia. Black tea is fully fermented and during this process, polyphenols are oxidised into pigments and may lose their antioxidant effects. Second, black tea is often served with milk, which previous research has shown may counteract the favourable health effects of tea on vascular function.

Gender-specific analyses showed that the protective effects of habitual tea consumption were pronounced and robust across different outcomes for men, but only modest for women. Dr Wang said: "One reason might be that 48 per cent of men were habitual tea consumers compared to just 20 per cent of women. Secondly, women had a much lower incidence of, and mortality from, heart disease and stroke. These differences made it more likely to find statistically significant results among men."

She said: "The China-PAR project is ongoing, and with more person-years of follow-up among women the associations may become more pronounced."

In conclusion, the authors have found that randomised trials are required to validate the results and to illustrate nutritional guidelines and advice for lifestyle.

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Agencies
June 27,2020

After admitting that the world may have a COVID-19 vaccine within one year or even a few months earlier, the World Health Organisation (WHO) on Friday said that UK-based AstraZeneca is leading the vaccine race while US-based pharmaceutical major Moderna is not far behind.

WHO Chief Scientist Soumya Swaminathan stated that the AstraZeneca's coronavirus vaccine candidate is the most advanced vaccine currently in terms of development.

"I think AstraZeneca certainly has a more global scope at the moment in terms of where they are doing and planning their vaccine trials," she told the media.

AstraZeneca's Covid-19 vaccine candidate developed by researchers from the Oxford University will likely provide protection against the disease for one year, the British drug maker's CEO told Belgian radio station Bel RTL this month.

The Oxford University last month announced the start of a Phase II/III UK trial of the vaccine, named AZD1222 (formerly known as ChAdOx1 nCoV-19), in about 10,000 adult volunteers. Other late-stage trials are due to begin in a number of countries.

Last week, Swaminathan had said that nearly 2 billion doses of the COVID-19 vaccine would be ready by the end of next year.

Addressing the media from Geneva, she said that "at the moment, we do not have a proven vaccine but if we are lucky, there will be one or two successful candidates before the end of this year" and 2 billion doses by the end of next year.

Scientists predict that the world may have a COVID-19 vaccine within one year or even a few months earlier, said the Director-General of the World Health Organization even as he underlined the importance of global cooperation to develop, manufacture and distribute the vaccines.

However, making the vaccine available and distributing it to all will be a challenge and will require political will, WHO chief Tedros Adhanom Ghebreyesus said on Thursday during a meeting with the European Parliament's Committee for Environment, Public Health and Food Safety.

One option would be to give the vaccine only to those who are most vulnerable to the virus.

There are currently over 100 COVID-19 vaccine candidates in various stages of development.

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