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San Diego, Apr 15: Several people lost their sense of smell or taste weeks ago globally and are still waiting for it to come back and now, researchers have identified an association between sensory loss and novel coronavirus 2019 (COVID-19) infection, indicating that loss of smell and taste may be considered as early symptoms of the deadly disease.

Interestingly, the study also found that persons who reported experiencing a sore throat more often tested negative for COVID-19.

The team from University of California-San Diego found high prevalence and unique presentation of certain sensory impairments in patients positive with COVID-19.

Of those who reported a loss of smell and taste, the loss was typically profound, not mild.

"Based on our study, if you have smell and taste loss, you are more than 10 times more likely to have COVID-19 infection than other causes of infection. The most common first sign of a COVID-19 infection remains fever, but fatigue and loss of smell and taste follow as other very common initial symptoms," explained study researcher Carol Yan from UC San Diego.

"We know COVID-19 is an extremely contagious virus. This study supports the need to be aware of smell and taste loss as early signs of COVID-19," Yan added.

For the findings, published in the journal International Forum of Allergy and Rhinology, the research team surveyed 1,480 patients with flu-like symptoms and concerns regarding potential COVID-19 infection who underwent testing at UC San Diego Health from March 3 through March 29, 2020.

Within that total, 102 patients tested positive for the virus and 1,378 tested negatives. The study included responses from 59 COVID-19-positive patients and 203 COVID-19-negative patients.

Encouragingly, the rate of recovery of smell and taste was high and occurred usually within two to four weeks of infection.

"Our study not only showed that the high incidence of smell and taste is specific to COVID-19 infection but we fortunately also found that for the majority of people sensory recovery was generally rapid," said Yan.

"Among the COVID-19 patients with smell loss, more than 70 per cent had reported improvement of smell at the time of the survey and of those who hadn't reported improvement, many had only been diagnosed recently," she added.

Sensory return typically matched the timing of disease recovery.

In an effort to decrease the risk of virus transmission, UC San Diego Health now includes loss of smell and taste as a screening requirement for visitors and staff, as well as a marker for testing patients who may be positive for the virus.

"It is our hope that with these findings other institutions will follow suit and not only list smell and taste loss as a symptom of COVID-19, but use it as a screening measure for the virus across the world," Yan said.

Mangaluru, Mar 21: Southern Railway has cancelled some more trains in view of poor patronage due to restrictions in place to prevent the spread of COVID-19.

Train No.16565 Yesvantpur-Mangaluru Central Weekly Express has been cancelled on March 22 and March 29.

Train No.16566 Mangaluru Central-Yesvantpur Weekly Express will not run on March 23 and March 30.

Train No.10215 Madgaon-Ernakulam Weekly Superfast Express will not be operated on March 22 and March 29.

Train No. 10216 Ernakulam-Madgaon Weekly Superfast Express will not run on March 23 and March 30.

Train No.16355 Kochuveli-Mangaluru Junction Antyodaya Express, scheduled to leave Kochuveli on March 21, 26 and on March 28 stands cancelled.

Train No.16356 Mangaluru Junction-Kochuveli Antyodaya Express, scheduled to leave Mangaluru Junction on March 22, 27 and March 29 will not be operated, a Southern Railway release said.

Hubballi–KSR Bengaluru–Hubballi Janashatabdi (Daily) Express (12079/12080), Mysuru–Yelahanka–Mysuru Malgudi (Daily Express)

(16023/16024), Yeshwantpur–Pandharpur–Yeshwantpur (Weekly) Express (16541/16542), Mysuru–KSR Bengaluru–Mysuru Rajyarani Express

(16557/16558), Shivamogga–Yeshwantpur –Shivamogga Express Special (06539/06540), Mysuru–Renigunta–Mysuru Weekly Express

(11065/11066), Mysuru–Sainagar Shirdi–Mysuru Weekly Express (16217/16218), Yeshwantpur–Mangaluru–Yeshwantpur Weekly Express (16565/16566), and Belagavi–Mysuru Vishwamanava (Daily) Express (17326).

Mysuru–Belagavi Vishwamanava (Daily) Express (17325) has been cancelled till April 1.

The services of Train No.16023/16024 Mysuru-Yelahanka-Mysuru Malgudi Express has been cancelled from March 20 to March 31.

Similarly, Train No.16557/16558 Mysuru-KSR Bengaluru-Mysuru Rajya Rani Express will not ply from March 20 to March 31, according to a railway release.

Train No. 17325 Belagavi-Mysuru Vishwamanava Express will not operate from March 21 to April 1 and the corresponding service of Train No.17326 from Mysuru to Belagavi will remain cancelled from March 20 to March 31.

The authorities have also cancelled the service of Train No.11065 Mysuru to Renigunta weekly express which was to operate on March 20 and March 27 and the corresponding service from Renigunta to Mysuru on March 21 and March 28.

Likewise, Train No.16217 Mysuru to Sainagar Shirdi weekly express will not operate on March 23 and March 30 and the journey in the return direction of Train No.16218 Sainagar Shirdi to Mysuru weekly express on March 24 and March 31 stands cancelled.

The railway authorities have cancelled the Hubballi-KSR Bengaluru-Hubballi Janshatabdi superfast express from March 20 to March 31 and the services of Train No.06539/06540 Yasvantpur- Shivamogga Town-Yasvantpur express for March 20, 24, 25, 26, 27 and March 31 stands cancelled.

The other trains cancelled for a limited period include Train No.16541 Yasvantpur to Pandharpur weekly express for its journey commencing on March 19 and 26 and the return journey on March 20 and 27.