May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
Comments
Damn sure. he misused power. He threatened. Not her fault
Sad incident. i feel something is wrong. why will she escape from the hospital
police should do proper investigation.
Policemen needs bigger punishment than ordinary people. Dont they have ethics
Policemen needs bigger punishment than ordinary people. Dont they have ethics
Shame on you chinnappa. You uttered a typical Indian mentality of judging the woman when she suffers a rape
Looks like she moved out at her free will and faced such consequence. her fault
Need to change punishment system. We need something that arise fear to repeat. like chopping head publicly
so many grey areas are there.. such as hospitals, offices, schools, police station. need to have something emotionless creature.. robots or something else inorder to keep safe our sisters
What is the difference between RSS and ISS, R and I? R for Rowdy, I for Intelligence, so Rowdy and Criminal is equal so do not compare, Criminal is Criminal, Intelligence is Intelligence.
Woman is safe in India during Modi rule (if i say woman is unsafe under Modi rule, i will be called an anti-national)
A woman was gang raped and later she went missing. But people here are fighting with each other in the name of ISIS, RSS, ISI.. shame on you people.
wow ! naren kotian what a brilliant statement........... you should join FBI better hhhhhhhhaaaaaaa...
Dear Mr. NAren... How exactly you know that? You must be a member of RAW or ISI or ISIS or RSS I guess.
ISIS or its associate in India RSS must be behind raping this innocent girl. Israeli Secret Intelligence Service (ISIS) head SIMON ELLIOT (fake name Abu Bakr Baghdadi), Jewish actor trained by MOSSAD in terrorism and the same MOSSAD has been associated in training RSS - terrorists.
ISIS hand cannot be ruled out. people belonging to one particular community do all criminal activities posing as different people. Here they dressed like police and committed crime.
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