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May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.

According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.

"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.

They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.

Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.

"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.

"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.

In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.

"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.

The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.

These children were then confirmed to have COVID-19.

While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.

Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.

According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.

"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.

Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.

While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.

However, he cautioned that more research is needed to confirm their findings.

"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.

Bengaluru, Jun 24: About 8,48,203 students will appear in the Secondary School Leaving Certificate (SSLC) examination tomorrow, i.e., June 24, said Karnataka Health Minister B Sriramulu on Wednesday.

Students have been advised to report to the examination centre three-hour before the commencement of the examination i.e., at 07:30 am. The examination will commence at 10:30 am.

Early entry to the centres will also help maintain social distancing that is very much essential during the pandemic, minister for primary and secondary education S Suresh Kumar said.

"SSLC exams to take place tomorrow. About 8,48,203 students will write the exam. Social distancing needs to be followed and the mask should be used. Minister of Education and I have already held a lot of meetings. Students from containment zones will be carefully handled," said Sriramulu.

Commenting upon the situation arising in the state due to COVID-19, Sriramulu said, "There is a panel of experts to decide about lockdown. There has been an opinion that the COVID-19 test should be increased. Workers, traders, and others should be categorised in 15 categories and tests must be conducted," he added.

Sriramulu further said that there will be a meeting of task force on the coming Monday.

"All the issues will be brought to the notice of the Chief Minister at the task force meeting, then CM will take a call on what needs to be done," he said.

Meanwhile, Suresh Kumar, Minister of Education inspected the schools and places where SSLC exams will be held.

Earlier Karnataka Education Minister S Suresh Kumar had announced that SSLC examinations, which were stayed in view of the coronavirus pandemic, will be conducted 'between June 25 and July 4' in the state.

According to the Union Health Ministry, Karnataka has 9,721 COVID-19 cases including 150 fatalities.

Bengaluru, Jun 20: A 56-year-old head constable, who had tested positive for the coronavirus infection a couple of days ago and was undergoing treatment, died on Saturday, police said.

The deceased, attached to the Kalasipalya police station, was being treated at Victoria Hospital here, they said.

This the second death of a policeman in the state due to COVID-19. The first one was an assistant sub-inspector attached to the V V Puram traffic police station.

Officials said the deceased constable was among nine others who had tested positive for COVID-19.

Meanwhile, an ASI with the Wilson Garden traffic police station here has also reportedly tested positive. According to sources, the ASI is undergoing treatment at a designated hospital and the station has been sanitised. His contacts are being quarantined.