Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.
However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.
New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.
The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.
It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.
"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.
As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.
"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.
"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.
To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.
At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.
Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.
In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.
They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.
Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.
The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.
Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.
Comments
this is really foolish to give this kind of advertisement. Kanhaiya is getting free marketing out of fools like this. Very soon he will be famous & become politician too. When Aamir khan PK was released, some fools in Gujrath did marketing for PK movie by putting ban on the movie. This is also gonna be same. Already Kanhaiya is famous but the person who announced this money has given positive review towards JNU President. Now People all over India will know JNU president is Clean without any black mark on his career
Dear Randeep, you should read the news everyday it is officially declared that 60% RSS Goons are there in our Police force what more you can expect from them, it is clear that RSS and even BJP should be banned and we need a good government to rule the country not this fake, uncivilized and lyre BJP Govt.
A speech by Comrade Kanayya is revolutionary and praise worthy. Every Indian citizen must watch his speech in JNU campus. And his chat with Barkha Dutt, NDTV, unbelievable. His thought are very high for his age and his heart for the downtrodden, dalits, ST/SC/and minorities is praise worthy.
By announcing the reward for his killing or cutting his tongue clearly indicates Sangh Parivar and BJP's real intentions and their role in his sedition case.
Long live Kanayya,
RSS cannot stop people from speaking from their heart...independent India gave all its citizens right to speak, nobody can curtail that right from anyone....if they kill one Kanhaiya, there will be more of him born in India....it will be multiplying...how many they will kill...forget about 13 lakhs...13000000 crores will not be enough for it....
WE WANT AZAADI FROM RSS
WE WANT AZAADI FROM VHP
WE WANT AZAADI FROM ABVP
Ban RSS
What else to be expected from the Terrorists ???
Killing, Bloodshed, Riots, Rape threats to women, Disturbing Peace, Attacking religious places, Attacking lonely and even Old Aged, Harassing Innocent People .......... What not ?.
They have forgot that Death will not come to them ?
A Cheddi deception to put u in trouble just like Godse..
No one will get this money... Black money still on que
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