May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
Comments
Congratulation Harinath!! all the best for your future plans.
So many rejected votes that means so many elected representatives whichever party they belong not educated enough at least how to vote. One who vote them has to be blamed. what work they can do for the betterment of the society. The majority of the winning candidate to knows raise two fingers only while they win.
jai jai BJP, Congrates Sumithra all the best.
Congratulations & All best wishes to our New Mayor harinath. Let Mangalore develop under your leadership.
Congratulations to deputy Mayor too. jai ho congress.
Look at our Photo obsessed congress leaders of Mangalore namely Bava & Vinayraj. Pushing and posing is their birthright.
Give first priority to invent Cancer (communal riots) treating medicine which is taking lot of innocent lives in Coastal area due to some dangerous virus spreading it. If you succeed in this you will be remembered as a best scientist in the History.
Congratulation......Keep going...All the best.
Congratulations to the newly elected Mayor and Deputy Mayor.
Finally we got a mayor.
Congrats to both of you.
Congratulations on being elected as new Mayor for MCC. Do your best to take this city as the best city in the state.
Hope new mayor won't use dhow as done by earlier mayor during flood..as a joyride..!!
Congratulations harinath, you deserve this after serving long years and we look forward your good works and smiling face.
Next What????? making money ya making developments?????
Congratulations Mayor and Deputy Mayor. God bless you both and all the best
Congratulations harinath, I am sure you will work for the development of Mangalore, specially on drainage and drinking water. May God be with you and grant you good health to work for the welfare of the people.
All credit goes to Khader, Lobo, Raikulu.....Congis worried about vote bank as all states are sweept by BJP and they are looking to retain Karnataka with the help of Minorities!
This is your mission to serve the city without looking your pocket, but serve the city with selflessness.to maintain safety in the region......don't look for the party and religion but serve as human.All the best
Please work enthusiastically, united, share each other, bring amicable solution for the problems,include innovative practices, future plans, keep vision Goal and mission.
Unnecessary Politics. Groupism should be banned. It is very unhealthy in the community.
Election is over. Sink your differences. All the members have the mandate to work together as a NEW TEAM to the steady growth of the MCC at the out set of the financial 'crisis. I wish all the best to the new mayor
All the best to the newly elected mayor of MCC. Hearty congratulations to all,
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