Soldiers are actually dying because of politicians: Shehla Rashid

Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.

However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.

New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.

The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.

It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.

"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.

As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.

"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.

"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.

To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.

At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.

Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.

In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.

They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.

Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.

The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.

Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.

Bengaluru, Jul 16: Amid difficulties being faced by COVID-19 patients in getting beds, the Karnataka government on Wednesday made bed allocation display board mandatory in all hospitals registered under Karnataka Private Medical Establishment (KPME).

"It is made mandatory that all hospitals registered under KPME in Karnataka State should display at the reception counter, a bed allocation display board," a notification issued by the state government read.

"It should display the name of the hospital, the total number of beds (as per of KPME registration) and the total number of beds allocated for COVID-19 patients referred by Bruhat Bengaluru Mahanagara Palike (BBMP)," it said.

The notification further stressed that the data must corroborate with the data of the central bed allocation system of BBMP. The display board should be arranged by July 16.

Non-compliance to the order issued by the state government will attract punishment under relevant sections of the Disaster Management Act 2005 and Indian Penal Code, the order read.

The state government on June 23 issued a notification making it mandatory to reserve 50 per cent of the beds in private hospitals to treat COVID-19 patients referred by public health authorities.

Bengaluru, Jul 5: Day after a Covid-19 patient died on a road near his home waiting for an ambulance for nearly two hours, Bengaluru civic body commissioner on Saturday offered his unconditional apology for the tragic incident.

Bruhat Bengaluru Mahanagar Palike (BBMP) Commissioner BH Anil Kumar met the family of the 55-year-old Covid-19 victim who died unattended on the roadside on Friday and apologised on behalf of the BBMP.

BH Anil Kumar also appealed to citizens to not stigmatise coronavirus patients and their families.

"Met the family of the Covid victim in Gavipuram who was left unattended on the roadside. Offered an unconditional apology on behalf of the BBMP as our staff could have handled the situation in a better manner. Appeal to citizens not to stigmatise Covid-19 patients & families," BH Anil Kumar said in a tweet.

In one of the pictures tweeted by BH Anil Kumar, he can be seen standing with folded hands in front of the deceased Covid patient's family.

The 55-year-old man was getting treatment at his house after he developed breathing issues. However, his condition worsened after his Covid-19 report came positive. His wife then informed the hospital and requested an ambulance.

His family members decided to take him to the hospital by an autorickshaw as the ambulance was getting late. However, the man collapsed on the street as soon as he stepped out of his house.