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May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.

According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.

"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.

They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.

Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.

"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.

"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.

In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.

"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.

The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.

These children were then confirmed to have COVID-19.

While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.

Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.

According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.

"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.

Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.

While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.

However, he cautioned that more research is needed to confirm their findings.

"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.

Bengaluru, May 8: Karnataka Medical Education Minister Dr K Sudhakar along with Home Minister Basavaraj Bommai on Thursday visited Kempegowda International airport for inspection of the screening facility as over 10,000 people from Karnataka stranded in other countries are scheduled to arrive in the state. 

Sudhakar said all safety measures have been taken for the screening and quarantine of all passengers in hotels, hostels, and school buildings.

He appealed to local residents not to panic as adequate safety measures are being taken to prevent any spread of COVID-19 infection.

Thiruvananthapuram, Jun 25: The government of Kerala under the leadership of Chief Minister Pinarayi Vijayan is all set to launch the 'Kerala Dialogue' -- a debate series on new concepts and development models during the COVID-19 pandemic.

A series of visionaries including noted political thinker Noam Chomsky and Nobel-laureate economist Amartya Sen will join this unique initiative that is to be rolled out from Friday.

The debate series to be inaugurated by the CM will feature prominent personalities from various walks of life including scientists, philosophers, diplomats, economists, writers, journalists, activists, technocrats and people's representatives.

The first episode will have Chomsky, Sen and WHO Chief Scientist Dr Soumya Swaminathan speaking on 'Kerala - Future Paths of Development'. 

State Planning Board vice chairman VK Ramachandran and senior journalist N Ram would be the moderators. The first episode would be telecast through the Chief Minister's official social media accounts.

The coming episodes in the series will also be telecast in the same manner. The government is of the view that the Kerala Dialogue series can ensure debates and dialogues on sustainable and inclusive development on the lines of the Kerala model.