May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
Comments
All that is on earth will perish, but face of your Lord will abide (forever) full of majesty, bounty and honor - Holy Qur'an 55:26-27
Nobody like rulers, bureaucrat or any citizen is bothered or cares such accident specially in Mangalore.
Human lives have no value specially for 2wheelers.
We are talking many projects in our area.
This is daily disaster. If we wish we can prevent such accidents with some good planning.
Such accidents are not UNPREVENTABLE.
If we want to allow our people to use 2wheelers, first we should plant to prevent and how to escape from these accidents.
Otherwise we all should by law or by force avoid using such vehicles.
At least our leaders in the city like DC, SP, RTO, MP, MLAs, Ministers, all those who use 2wheeler, please wake up and do the doable thing to save our people's lives.
Sad incident....... RIP
RIP... Feeling very sad... :-(
we CONDOLE but anybody thinking about death and do GOOD and stop evil... those who do good & recognise the true CREATOR, and submit to him to find the everlasting heaven.. which is the gift that God gives those who recognize him & follow his & his prophet's command..
My heartfelt condolences to you and your family. I will surely miss the presence of a truly loveable and kind person.
I am deeply saddened by the loss that you and your family have encountered. My condolences
It’s terrible to hear about, my sincere sympathy to your family.
this bus drivers are very rude on the road, put him behind bar for atleast 20years. he is a real murderer.
You and your family are in our prayers. Sorry to hear of your loss mam.
Our hearts are saddened by your loss and our thoughts and prayers are with you
My deepest condolences for your family's loss.
really sad, she s one of the good lecture in our college, we really gona miss her a alot. love u mam
Heartfelt condolence to the family, nobody can pay the loss to the family.
JESUS SAID :
The father is greater than I - John 14:28
The Lord our God is ONE LORD - Mark 12:29
By myself I can do nothing - John 5:30
I ascend to my Father & Your Father - John 20:17
PAUL SAID :
Jesus is equal to the father
God exists as 3 persons
Jesus is all powerful
Jesus is the only son of God..
Recognize Who speaks WHAT? A thought for the thinking Soul.
Really Tragic ! just before 6 months she joined as a lecture in agnes all her dream went in vain because of this half finished road.
Add new comment