May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
Comments
Naren
terrorism started from Sikhs not Muslims and till today your people only following it. No need to teach matured person like you so understand the logic of your people.
Is constitution said to make illegal relationship with ladies without marrying them to fulfill your desire? Is your community got the message from constitution to rape in the bus and to kill innocent girl? Constitution made for good will of the citizens not to torture them.
there is no deference between you and Israel but remember we fear Almighty.. Not you or them!
rikacha , nimma root navare kanri , foot alla ... hahaha ...
You cannot expect more than these goondas who dont heistate to worship anything. they don't know what is God
Here we cant show patience or silence.
When justice fails, then Tit for tat is only the ultimate solution.
constitution dont say u can marry 4 , constitution dont say u can do terrorism , killings , rapes , but ur community does it . then whats the problem in telling this ... first of these three rogues are not indians , they look like pakistanis ...isis barodakke they are creating launch pads , but nationalist indians are there to protect hindus , sikhs and christians ..nam deshadalli yaava kumda salafist backed isis nadiyalla ... anybody questions our nations integrity will be strongly dealt with . Muzzies are thinking by doing this they can bring down modi from PM post . no ... not at all possible . there is a deep polarisation even in villages it isnow being felt . by 2024 , India will be hindu rashtra for sure . to amend constitution 2/3 majority needed and all states if we make congress mukht we are done . with coopearting with israelis , defintely we can achieve this . ummah is so weak that it is already divided , no body has guts to speak against India if it does so ... even if they speak , millitarily they are not on par with India .gulf countries want USD from India , for their cheap petrol . hahaha
No one can change the faith by forcing anything.
bitter truth for RSS
Very dangerous for the future of India. Rising intolerance, forcing others what one practices, poking nose in other's matters, dictating what to eat what to wear, all these will eventually lead to sectarian fights, genocides, civil war etc., India may end up in situation similar to Iraq and Iran. BJP sarkar and Sangh parivar must control their bhakts before it is too late.
Constitution even did not say to eat or drink :P
By looking at their face they look very papa, but they raised voice against what other side party asked. strange but true.
What if they call Jai Mata Di or not?
accused must be punished who are they to beat the innocents.
my foot....
Its Their Wish any constitution dint asked all the citizen to call anything particularly.
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