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Bengaluru, Feb 19: Playing down the simmering discontent among the disgruntled legislators who missed a cabinet berth again, Karnataka BJP on Tuesday denied any revolt brewing against Chief Minister B.S. Yediyurappa.

"An unsigned letter in Kannada circulating in the social media is bogus, as it was fabricated in the name of Santosh, a private secretary to Yediyurappa. No revolt is brewing against the Chief Minister," party spokesman G. Madhusudhana told news agency here.

In the second cabinet expansion on February 6, only 10 newly-elected legislators, who defected from the Congress and the Janata Dal-Secular (JD-S) in July, were inducted, leaving the party's many aspiring lawmakers miffed.

"The talk of about 20 loyal MLAs ganging up against Yediyurappa is a speculation as rumour mills are working overtime. No rebellion is brewing against the Chief Minister," asserted the official.

On the charge that Yediyurappa's younger son B.Y. Vijayandra was acting like a 'super or de facto CM' and medalling in the state administration, Madhusudhana said the latter was only assisting his father in party activities as he was also a party worker.

"As Yediyurappa is 76 years old and ageing, Vijayandra is helping his father in party affairs so that he (Chief Minister) could be free to attend to administration," Madhusudhana said.

Yediyurappa's elder son B.Y. Raghavendra is a three-time BJP Lok Sabha member from Shimoga in the state's Malnad area.

With six cabinet posts vacant in the 34-member ministry, many legislators, including eight-time MLA Umesh Katti, are upset that they have not been rewarded for their loyalty to the party even six months after the BJP returned to power again in the southern state.

On the purported meeting of about 20 BJP MLAs at the residence of state Industries Minister Jagadish Shettar here on Monday, Madhusudhana said it was a "get-together" as they were all in Bengaluru again to attend the budget session of the state legislature which began on Monday.

"There is no crisis in the party. Our government is stable and will complete the remaining three-year term in office till May 2023," he added.

Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.

However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.

New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.

The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.

It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.

"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.

As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.

"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.

"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.

To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.

At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.

Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.

In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.

They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.

Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.

The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.

Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.

Mangaluru, Jul 19: Two flights with 346 stranded Kannadigas from Sharjah and Dammam landed at Mangalore International Airport (MIA) on Saturday night.

MIA officials said on Sunday that the chartered flight from Dammam landed with 178 stranded people, while an Air India flight from Sharjah landed with 168 stranded passengers under the 'Vande Bharat Mission'.

All the passengers on their arrival underwent health checkup and were sent for seven days institutional quarantine. They will undergo swab tests during the quarantine period, health officials said.