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May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.

According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.

"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.

They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.

Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.

"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.

"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.

In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.

"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.

The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.

These children were then confirmed to have COVID-19.

While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.

Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.

According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.

"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.

Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.

While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.

However, he cautioned that more research is needed to confirm their findings.

"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.

Bengaluru, Mar 30: Chief Minister B S Yediyurappa on Sunday convened an all-party meeting and apprised the Opposition leaders about the measures taken by the government to contain the coronavirus in the state.

"I have been regularly holding meeting since March 13 regarding the measures taken to contain the transmission of COVID-19," the chief minister said at the meeting at the Vidhana Soudha.

Health Minister B Sriramulu, Medical Education Minister Dr K Sudhakar, IT-BT Minister C N Aswath Narayan, Deputy Chief Minister Laxman Savadi, former chief minister and Leader of the Opposition Siddaramaiah, Opposition MLAs H D Revanna, D K Shivakumar and former speaker K R Ramesh Kumar attended the meeting.

The chief minister said a task force comprising ministers and officials has been formed to oversee the implementation of the government orders.

Yediyurappa highlighted the prevailing situation across the globe saying that normal life had been paralysed everywhere.

The chief minister also apprised them about the number of clinics all over the state, availability of medicines and protection gear for the doctors and quarantine rooms in the state.

Bengaluru, Jul 17: Bruhat Bengaluru Mahanagara Palike (BBMP) Mayor, M Goutham Kumar on Friday called for an extension of lockdown in the city for one more week due to rise in the COVID-19 cases.

"It will be better if we get more time to tackle COVID-19 cases, we wish for the extension of lockdown for one more week. We have given the proposal to the government," said M Goutham Kumar, BBMP Mayor.

"After the number of cases increased in Bengaluru, BBMP started antigen test in containment and hotspot zones of Bengaluru to tackle the cases which have crossed 2,000 mark," he added.

Along with Mayor, BBMP Commissioner Anil Kumar has also proposed the state government to extend lockdown in Bengaluru for one more week.

"The number of cases in Bengaluru increasing in Bengaluru rapidly. BBMP has inaugurated more than 200 vehicles in Bengaluru for the use of the antigen test," said Anil Kumar, Commissioner BBMP.

According to the Union Health Ministry, there are 51,422 COVID-19 cases in the state.