May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
Comments
who cares? go to hell
Media made her popular. No valve for this award. I strongly support raviji for this.
I wish that in your next birth you born as a girl in a backward country like Pakistan or Afghanistan , and if then you are able to raise your voice after being shot at and then if you still stay strong and become an inspiration to millions and the word then and only then would you deserve the respect that your are seeking so desperately.
Malala was also a western drama.... More people deserve to be honoured..... But why shriji just opposed malala only..... Shows comunal mentality clearly
I agree with Ravishankarji.
I agree with Ravishankar ji.
Bro Mohammad, #2
There is medicine for JEALOUSY, HATE, CRIME, EVIL habits... But the person should take the change to change himself.
Let the Jealous person read the biography of Prophet Muhammad Pbuh. and also let him read the QURAN which is the Guidance for humanity and how to live life according to the law of God. JEALOUSY will run away automatically if We PONDER on what DIVINE knowledge says to us.
Mr sri sri sri
We all know that your work/service doesn’t come free free free
It’s not a Nobel Prize offer Mr sri sri sri we all know that, at the most, it might have been just a nomination for the prize, which are in hundreds and this information is for you for free free free
He is the no. one duplicate & feku. any one shake him well all his originality will come out. No doubt one day will be soon.
Master Ravi Jeeee First I Thought would have our Great Leader Master Scorer C T Ravi jeee he is right person to award Nobel Peace award. any way Sri / Siri says he was rejected and against to Ms Malala's selection, you all surely know very well, Malala totally un fit to award it but discriminated fools around the world chosen not Maste Narendra Modi selected Ms Malala because you all fools of this criminal minded world knows against of a group or de polarise the entire group. Sri Sri is good to magic man in this world making beautiful woman Fools.
Jai Hoo Narendra Modi.
They gave noble prize for Obama, for what???....I did not find any reason for it....Malala is an inspiration and hope for millions of underprivileged girls around the world...
Really... these awards should be given to Narendra Modi, Mohan Bhagwat, for their rolE to implement successfully Acche din in the country, if this award would have been given to Ravishankar could be better also...Now all are silent this fellow started Barking
Malala Yousafzai has done nothing to deserve Nobel Peace Prize
why did you congratulate #Malala two years ago if you don't think she deserved the @NobelPrize?
WHO CARES FOR U SRI SRI SRI ,
BEC U RAISED THE SLOGAN PAKISTAN ZINDABAD PLEASE GO TO PAKISTAN U HAVE NO RIGHT TO STAY HERE ANYMORE ....
I agree with him. I love Malal for her bravery, but when it comes to Nobel prize what was her contribution?
100% i Agree With Shri Shri Ravi Shanker....
After being shot in the head.. she is still fighting for the rights of girls and children.. you say that she is not deserving one.. then who deserves more??
Shri Shri Ravishankar please stop your non-sense,
This swamiji dont have any work simply putting nose to everything. if this swamiji dont want any award let him sit at ashrama, there is no rule to follow him,
Ravi shankar received padmavibhushana this year,
There is no Medicine for JEALOUSY. Dont waste your precious time try to learn about ISALM. And be prepared for your Future.
Dear Sri,
First pay the Pending TAX to the Govt then give the lecture.You did right thing of giving back the Nobel prize as you your self know that you really dont deserve.
He is a Man with Two Faces.
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