Forget rivers and dams; groundwater too reaching danger level in Mangaluru

May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.

According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.

"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.

They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.

Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.

"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.

"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.

In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.

"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.

The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.

These children were then confirmed to have COVID-19.

While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.

Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.

According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.

"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.

Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.

While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.

However, he cautioned that more research is needed to confirm their findings.

"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.

New Delhi, Jun 8: Two civil defence employees have been arrested by the Rajasthan Police today in Jaipur based on Military Intelligence (MI) inputs that they had been passing on sensitive information to Pakistan's spy agency ISI.

The arrested are: Vikas Kumar (29), a civil defence employee at an army ammunition depot near Shri Ganganagar (Rajasthan) and Chiman Lal (22), a civil contractual employee of the army's Mahajan Field Firing Range (MFFR), Bikaner. 

Both were working as espionage agents on behalf of Pakistan's intelligence agency and were giving out details of Ammunition and MFFR, vital military installations in India's Western front. 

The MI Lucknow's operation named Desert Chase assumes great importance as the Shri Ganganagar Ammunition Depot and Bikaner MMFR are strategically important military installations on the western front along the Pakistan border.

The work on the "operation" began in August 2019, when the MI Lucknow, through its sleuths, learnt about an espionage agent near Sri Ganganagar who was passing military information to his handlers in Pakistan. The individual was identified as Vikas Kumar - the civil defence employee at an army ammunition depot near Sri Ganganagar.

The MI Lucknow shared the case with UP ATS in the month of January 2020. Vikas's activities were monitored and analysed by a joint team of MI Lucknow and UP ATS. The operation was code-named 'Desert Chase'.

Based on these, it was learnt that Vikas is acquiring photos of a "water distribution register" at a water point/pump house in MFFR through a contractual civil employee named Chiman Lal. The development of the case was halted due to the start of the lockdown period all across the country.

Finally, the case shared with Rajasthan Police Intelligence in the first week of May 2020. A joint team was formed between Rajasthan Police-Intelligence and MI Lucknow.

Fresh leads were found as new payments were detected along with a trail of sensitive information being passed on to Pakistan by two accused.  

Vikas Kumar confessed to having passed the following information to Pakistan:

•    Details received from Chiman Lal about Army units and their strength coming to MFFR.
•    Details of ammunition coming to his ammunition depot including their type, quantity, mode of transportation, date of arrival on a routine basis (almost every time it came to his notice).
•    Details of ammunition (to include their type, quantity and mode/date of transportation) further distributed/transferred to local army establishments/units (including two local brigades) and elsewhere from his ammunition depot.
•    ORBAT (Order of battle; composition related details) of two local army brigades and all changes in them as they came to his notice.
•    Name, rank and personality traits of some Senior Military Officers in the two army brigades nearby, his ammunition depot and others who visited the military station.
•    Photos of arms, ammunition, tanks other military vehicles (with their tactical numbers) at MFFR whenever he could visit it after April 2019.

Vikas also confessed to having received at least Rs 75,000 in total from his Pakistani handler for the information he has shared during this entire period. He used to receive them mostly on bank accounts of his and his brother, Hemant Kumar. The latter was found to have no links to the espionage case otherwise. Out of this sum, he had paid approximately Rs 9,000 in total to Chiman Lal for his assistance in lots of Rs 1000- Rs 2000 since their first meet.