May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
Comments
If india gives him same punishment then assume that india is developed, in india criminals are given more respect than the victims.
Insane person. why dont you give him similar punishment....
Leave Bihar Campaign :)
Is controlling criminals important or fighting against Modi important? Nitish and KC Tyagi, please tell us
Shameless act from a political goonda. BTW had it been a BJP politician's son, CD would have had BJP in the headline. No I am not condoning the act if it was a BJP politician's son involved, I am just talking about how biased this channel is.
if the leader in the SUV was a BJP leader, your headline would have screamed the word BJP. Bajrangi RSS etc!
That politician's son is going to be get caught and will soon be released without facing any punishment.
that's how it happens in India!!!
in case of BJP politician, headline would have been ' BJP politician shoots 19 year old boy'. Since crime is committed by a non BJP politician, it only says politician in hearing.
This how the journalists manipulate the news.
Biharis Deserves... who voted corrupt Goonda Rajya
CM Nithish Kumar is in Kerala, he want the Kerala to be made same like Bihar.
Nitish Kumar is busy trying to cobble up a coalition in his desperate attempt to become the PM of this country. Meanwhile, the state is ruled by Lalu and his sons. So the jungle raj continues in Bihar.
its time to make bihar, up, wb ,delhi and kerala as independent nations. kick all these aholes from rest of india, let them solve their civility issue themselves.
gutter people
THERE IS TOTAL JUNGLE RAJ PREVAILING IN BIHAR SINCE LAST 25 YEARS DURING RJD- JD(U) MISRULE. NITISH KUMAR IS RUNNING GOVT WITH HELP OF CORRUPT MEDIAS WHO ARE GETTING HUGE MONEY I.E. HUNDREDS OF CRORES PER ANNUM FROM JD(U) GOVT FOR FLASHING ROSY PICTURE OF CORRUPT AND WORST NITISH GOVT. LALOO HAS RETURNED REIGN OF TERROR IN STATE WHERE HIS COMMUNITY IS INDULGED IN MASS ANTI-NATIONAL ACTIVITIES LIKE NAXALISM, MURDERS, DACOITIES, KIDNAPPING ETC. THIS IS BEYOND CAPACITY OF CM TO CONTROL IT. SO PEOPLE OF BIHAR IS BOUND TO SUFFER FOR ELECTING CORRUPT AND WORST PERFORMING GOVT WHEN THERE WILL BE NO PEACE AND PROSPERITY.
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