May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
Comments
@#14 Mohammed Saleem, Sharjah,
You have a block in your mind blocked the of evil. Once made a shahadah the evil enters your heart and mind to go to Madrassa.The Madrassas are teaching against Hindus, Christians, and Jews. Are you kidding, Islam
After many messengers were sent... and conveyed the message of ONENESS of God... ALLAH sent MUHAMMED pbuh as the last and final MESSENGER to the people to convey the same one MSG of WORSHIP the creator not his CREATION .. WE should not worship EVEN prophet Muhammd pbuh...
ALLAH Revealed QURAN to Muhammad pbuh as BIBLE for JESUS and TORAH for MoSES...
Mohammed was not the first but he was the last messenger of ALLAH... Hope this might help dear PREM PRASAD unless YOUR HEART is not HONEST to know about the CREATOR who created all that exists.....
BE sincere and honest, ALLAH guides those who truly look for him.
Prem Prasad
If you don't understand something it doesn't mean it not exist.
Islam means Peace aquired by submitting your will to God. .
It exists right from beginning
Prem Prasad.
Islam means Peace aquired by submitting our wills to God.
And it exists from beginning of mankind.
If you don't understand something. It doesn't mean it don't exist
Islam is not just Arabic word. It means submission to God and obey his commands. Adam, Moses, Jesus and Mohammed peace be upon all submitted their will to God. Islam exist from beginning. Don't make God so cheap. He is lord for all from beginning till end. No other like him. Don't make image of God and compare to anything
@#11 Mohammed Saleem, Sharjah
You have to argue without logic in a circular manner. World was unknown to the word Islam Prior to 1400 or prior to 1st century. Why did you threw out the 10 commandments of God from O.T. Where was the Term Allah prior t
The only religion is accepted in front of God is Islam.
Islam means total submission to God.
To live according to commandments of God, which he sent time to time in each area through his messengers.
Islam started from first person in earth prophet Adam PBUH.
What was the name of your God prior to 1st century. The word Islam was not prevalent prior to 1400 years. Name Islam prevailed after Arabic was invented in the 1st century. III caliph Uthman is the editor of Quran. He destroyed all the manuscripts given by so-called Gabriel. To which place you were facing and praying prior to 1400 and had you been fasting prior to 1400 years where there was no month called Ramadan. The last prophet to humanity was Joseph Smith of the Mormons religion. 124000 prophets are illusions including false prophets. Don't tell me to read Quran. No need to read any book if a person is living a righteous life.
@Prem Prasad. Islam was not created 1400 years ago. It is a big mis-conception among many non-Muslims. 1400 years ago it was the final installment of the series of prophets (peace be upon them all) and revelations sent to human being by Almighty God. We b
Dear Brother Ahmadi / Asi...
Please make following Dua, U will understand everything...
O ALLAH, make what you teach me beneficial, teach me what is beneficial, and increase me in knowledge...
Allaahumma-nfanee, bimaa allamtanee, wa allimnee maa yanfaunee, wa zidnee ilmaa (Attirmidi # 3599)
Ramadan is the month in which MUSLIMS all around the WORLD fast for 29/30 days from dawn to dusk.
Fasting is the fourth pillar of ISLAMIC FAITH
The fast is an act of deep personal WORSHIP to get closer to ALLAH (God Almighty)
It is the month in which the QURAN was revealed to Prophet Muhammad pbuh.
QURAN chapter 2 Verse 183 says : O believers! The fast has been prescribed upon YOU just as it was prescribed for the followers of the Prophets BEFORE YOU, So that YOU may attain TAQWA (Piety)
Prophet Muhammad pbuh said, ALLAH said \All the deeds of man are for himself except for FASTING, which is for ME and I shall reward it Myself...
May ALLAH accept our Fasting and reward as he promised... ALLAHU AKBAR...All praise is to ALLAH, the Lord of all that exists.."
ASI DUBAI sawal acha hi but unfortunately till date no one answered for this question from last 10-15 years.
Where the Moon is sighted ???
Arabic was invented in the 1st century. Prior to 1st century to wich place you were facing and praying. Prior to 1400 which book you were reading and what was the name of your God before the 1st century.
Happy Ramadan and may Allah (SU) Bless us all in this Holy Ramadan....
\Allahumma ballighna ramadhaan\"
O allah makes this ramadhan easy for us\"
Join us to say aameen...."
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