2 die after boat capsizes; Muslim youth sacrifices life to save Hindu fishermen

Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.

However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.

New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.

The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.

It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.

"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.

As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.

"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.

"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.

To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.

At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.

Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.

In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.

They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.

Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.

The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.

Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.

Bengaluru, Jan 22: The Bengaluru Police on Wednesday said that the procedure is being followed to hand-over to the Mangaluru Police a suspect who surrendered before it two days after planting an improvised explosive device (IED) at the Mangaluru International Airport.

"He [the suspect] surrendered before police claiming to be responsible for the Mangaluru airport incident. He is being medically examined and we are preparing procedure to hand him over to the Mangaluru team which is already on their way," Bengaluru Deputy Commissioner of Police (DCP), Chetan Singh Rathore told the media persons.

Aditya Rao surrendered before Bengaluru Police today, days after a bag of IED was recovered from Mangaluru airport. He hails from Udupi and has engineering and MBA degrees.

An investigation team of Mangaluru police is flying to Bengaluru to question him. "Mangaluru city police investigation team is flying to Bengaluru shortly to investigate the developments in connection with MIA case..the team will question the suspect and will initiate further necessary legal action," Commissioner of Police, Mangaluru City, tweeted.

According to the police, the IED was recovered from a bag at Mangaluru airport on January 20. It was later defused in an open field by the personnel of the bomb disposal squad.

Bengaluru, Feb 5: New Tulu movie Pingara has bagged the NETPAC International Jury Award at the 12th edition of Bengaluru International Film Festial (BIFFes) on Wednesday.

Written and directed by Preetham R Shetty, the movie revolves around people who worship daivas (spirits) of Tulu Nadu.

The narrative goes back and forth in time, to tell the story of a family to Sinchana (Chaitanya Chandramohan), a journalist from Bengaluru who visits a village in Tulu Nadu to ‘write on Tulu culture.’

The film speaks about the caste system in Tulu Nadu and the struggle for land in the post-independence period.