Mangaluru hubby goes alone on Europe honeymoon; Sushma assures to send wife Sana!

Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.

However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.

New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.

The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.

It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.

"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.

As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.

"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.

"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.

To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.

At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.

Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.

In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.

They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.

Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.

The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.

Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.

Bengaluru, Jun 9: A 24-year-old who wanted to experience the feeling of death lost his life after consuming pesticide — he recorded it all on TikTok — in Koratagere taluk of Tumakuru district on Saturday evening.

Chided by his mother for not earning money, Dhananjaya, a resident of Gouraganahalli, on Saturday evening bought pesticide from a shop and shot a 15-second TikTok video, saying, “I want to experience the feeling of what death would be like. I will try to kill myself.”

Locals rushed Dhananjaya to a nearby hospital where he breathed his last the next morning. Koratagere police registered a case of unnatural death.

According to police, Dhananjaya had in the past rammed his Bajaj Pulsar bike into a tree to ‘experience’ death but had survived with minor injuries. Villagers and family members had advised him to not to take such risks. But he continued to do so as he was obsessed with death and posted his opinion regularly on TikTok, where he had 431 followers.

He tied the knot four months ago and was running an autorickshaw on rent. However, his earnings reduced to zero during the lockdown and he wasn’t mentally stable, claimed villagers.

Investigators said Dhananjaya wanted to scare his mother with his suicide threat and wanted to ‘experience’ death. He consumed poison near a farm but later panicked thinking he would die. However, he was not in a position to ride back home. He called his friend, who visited the spot and shifted him to hospital on Saturday night, police said.

Kolkatta, Mar 19: A local leader of BJP has been arrested for organising a cow urine consumption event in Kolkata, claiming that it will protect people from coronavirus or cure those already infected, leading to a civic volunteer falling ill after drinking it.

The police said that 40-year-old Narayan Chatterjee, who had on Monday organised a cow worship programme at a cowshed and distributed cow urine, was arrested following a complaint filed by the victim.

He had vouched for its "miraculous" properties while offering gaumutra to others.

A civic volunteer, who was on duty near the cow shed also consumed gaumutra and fell sick on Tuesday, following which he lodged a complaint with the police against Chatterjee.

Reacting to the arrest, the state BJP leadership criticised the state government.

"Chatterjee had distributed cow urine, but he didn't fool people in consuming it. When he distributed it he clearly said it was cow urine, he didn't force anyone to drink it. It has not been proved whether it is harmful or not.

"So how can just police arrest him without any reason. This is completely undemocratic," state BJP General Secretary Sayantan Basu said.

West Bengal BJP chief Dilip Ghosh has said there is no harm in drinking cow urine and he has no qualms in admitting he consumes it.

His party colleague and MP Locket Chatterjee, however, differed, terming it an "unscientific belief" that should be shunned.

The cow urine distribution as a cure for coronavirus had drawn sharp criticism from the doctors.