May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
Comments
he is the brother of mangalore information officer Khader shah, i think.
Good boy.. keep it up.. but don't exchange phone numbers ok??
THIS IS CALLED HUMANITY......PLEASE DONT MIX THIS INCIDENT WITH RELIGION....WELL DONE ASHRAF HATS OFF TO YOU..
PROUD TO BE MANGALUREAN....
something fishy is going around on this story... so I am confused with this story
Ma Sha Allha... Job well Done... Dear Haris Bhai,
He is the One Brother of My Close Friend he is Also well Social Worker,
KEEP IT UP BRO...
Mashallah... Well done Haris ,You gave a good lesson for humanity, when someone needs help caste,religion,gender will not come into consideration its only helping each other what it counts.. UR PERFECT EXAMPLE FOR BROTHERHOOD... :) ALLAH GIVE U SAFE HEALTH
The lady may be from a middle class or poor family, that is the reason she may be working as a sales girl. A gold chain may be for her a big asset, it is her hard earned saving money.
so good job done by Haris. Keep it up good work.
couple of Mangaloreans we may find thieves, robbers but 95% of Mangaloreans are good hearted people, who always help each other whenever any difficultly arrives to one another.
If every Mangaloreans do this act then the some particular groups who are jobless will need to find a respectful job. there are lot of looters who loot people in the name of a religion...
BRAVE WORK, APPRECIATED!!!
#7, ALTAF, DOHA, WHY U SEEING EVERY ACTIVITY IN COMMUNAL ANGLE????
chain snatcher trained by job less chaddi & sanghis how can they tolerate my dear brother althaf doh....
Robbery Jihad.. Some may be not happy by his bravery act..
This is how a Muslim should be.This is also Jihad
Where is Thief Photo?
Muslim guy helping Hindu Lady.. Chaddi & Sanghis can not tolerate this.
Excellent work by Mohammed Haris . keep it up
Good job Haris, you are brave.
The name Haris meaning itself is Guardian or Guard.
May Allah bless you
great example for those who Entertained in this kind of situation.
wow we must encourage this, govt should give the reward for his work so more people can come forward to help in these type situation.
because of this people we can roam freely in public. keep it up
appreciable good work haris.
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