Cows rescued' by vigilantes in coastal Karnataka end up in slaughterhouses'

Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.

However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.

New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.

The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.

It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.

"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.

As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.

"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.

"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.

To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.

At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.

Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.

In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.

They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.

Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.

The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.

Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.

Mangaluru, May 10: A special train carrying 1,140 migrant workers stranded here in the lockdown has left Mangaluru railway station for Jharkhand.

Dakshina Kannada MP Nalin Kumar Kateel and Vedavyas Kamath, MLA, were present at the railway station on Saturday night when the train left.

Kamath said the workers who had registered on the state governments Seva Sindhu portal were brought to the railway station in Karnataka State Road Transport Corporation buses.

A health check-up was carried out before they boarded the train.

The district administration also provided food packets and water to the migrants at the station.

Three more trains will leave from Mangaluru for Uttar Pradesh, Bihar, and Jharkhand soon, he said.

Meanwhile, in a statement, Dakshina Kannada Deputy Commissioner Sindhu P Rupesh said train services are being arranged for migrant workers who have registered their names on the Seva Sindhu portal.

The workers will be informed when trains are arranged to their destinations and they need not throng the railway station unnecessarily, she said.

Around 20,000 workers have so far registered themselves online, including 5,000 from Jharkhand, 3,000 from Uttar Pradesh and 4,000 from Bihar.

Hundreds of migrant workers had on Friday staged a protest at the central railway station here, demanding that they be sent back home.

The workers went back to their camps only after district authorities and police gave them assurance that trains will be arranged in three days.

Mangaluru, Jul 12: No decision has been taken regarding re-imposition of complete lockdown in Dakshina Kannada, according to district in charge minister Kota Srinivas Poojary. 

The minister's clarification comes following social media rumours about complete lockdown in the district from July 14 to contain the spread of coronavirus.

Speaking to media persons, Mr Poojary said that chief minister will hold video conference with Deputy Commissioners, MPs and District ministers of the state on July 13 at 11 am. following which a decision will be taken. 

He also clarified that the government will not cause inconveniences to people by taking any such decision all of a sudden. "People should not pay heed to rumours," he said.