Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.
However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.
New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.
The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.
It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.
"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.
As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.
"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.
"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.
To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.
At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.
Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.
In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.
They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.
Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.
The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.
Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.
Comments
God says there is no God but him alone. He also says in QURAN that those who associate partners with him will not enter Paradise which is eternal (No death there). An intelligent person will not take it as simple msg, He will check if it is really God speaking or any man made thing...
So this intelligent person will research and study the Quran, also previous scriptures (original bible & torah and there are some elements in Vedas) to know WHAT IS THE PURPOSE OF OUR LIFE?
When our intention is HONEST to look for the TRUTH, GOD who put soul in us and CREATED us will surely show us the Signs of HIM and those who got his guidance are really BLESSED...
If some Muslims wants to hide the non muslims of the TRUTH of associating partners with him ... it is HE is hiding the TRUTH with U non muslims of severe punishment for associating partners with him...
God is JUST he created us and we worship man made things ... isnt it right that people recognise this TRUE GOD and WORSHIP him alone.
Quran explain in Surah 114:
Say He is ALLAH, the one and only,
ALLAH , the eternal absolute,
He begetheth not Nor is he begotten
And there is NONE like unto HIM
VEDAS also says \NA TASYA PrATIMA ASTI - There is no image of God.
Krishna is just like human (So TRUE MUSLIMS cannot except him as GOD) . There will be some illiterate in the knowledge of God in Muslim community as well... It is either bcos of his weak faith or other reasons. God knows best what is their FATE...
But for ME ... I cannot deny GOD and join the party of associating partners with HIM ... O ALLAH save me from SHIRK and Save me from the HELL fire which is eternal (No death there too)"
i posted the one comments and my name is missing. please add it while publishing
Ideal worship is Haraam & Shirk. we believe there is only one creator and we cant see him. otherwise i could have joined and enjoyed these kind of get together along with my non Muslims Brothers. But being Muslim our first faith itself is One God and for him no partner and no family. But my family and me Love our Non Muslim Brothers and Sisters so much as our own family members.
Communal peace and harmony not by celebrating Krishna Jayanthi or Mohammed Jayanthi... It is completely prohibited in Islam even Prophet's (PBUH) birthday celebration.
We can bring communal harmony in the society by helping one another, understanding one another feeding poor people in all community.. Brotherly life in the society... Celebrating these kind of Jayanthi just for name sake..it is not acceptable at all..
Ramya should celebrate this and talk about unity of the society she always wanted to divide the both opposite community. be like a true Indian celebrated the everything comes to the life.
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