Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.
However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.
New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.
The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.
It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.
"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.
As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.
"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.
"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.
To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.
At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.
Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.
In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.
They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.
Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.
The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.
Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.
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Please be a muslim and stop going to dargahs, it is prohibited in Islam, Dargahs nothing but a grave, don't expect any help from deceased, seek help from Allah only, real muslims will never go to Dargahs.
Dear Non Muslim Brothers.
I was going through your comments.One thing i would like to clarify with you is that do not judge Islam by seeing other's rather try to learn later you can judge your own.Islam never entertain Darga or Darga Pooja it is the people who added in Islam for their benefits where as Allah almighty do not need any Mediator.Learn Islam before its too late.
Question to the trustee
Who is watching breast of female visitors?
Dargah is not meant for those who believe in \Tawheed\"."
Still it is better than doing Shirq.!
Stop doing shirq & Nobody will show you anything.
Pray to Almighty Allah Only.
First of all true religious lady will not visit any dargah ( major shirk) which is haram in Islam.
Secondly how Muslim lady mingle with gents in any public or private place which is also haraam in Islam.
Thirdly looking at ghair mahrum is also haraam in Islam.
So all are eagerly awaiting to do haraam things in life!!! Shabbash...
@ Monu.. have you been to Haji Ali Darga.. go and see how many non-muslims come there and prostrate.. or else the Dargah should pass a rule for all.. to cover oneself with shawl or something to avoid such incidents
Haraam it is Shirkh for Muslims to pray in Dargah or visit it.
Mr. L.K. Monu
They are referring to non-muslims women entering dargah.,
Dear Reader.
In Islam women (compulsorily) should wear full covering cloth including all the parts of the body, leg and hand and except only face and 2 palm.
So where is the question of showing breast.
Note: Praying is normally include Rokooh and Sujood i.e. bend the body and Prostration and which is only for Almighty Allah not to Shrine of Bukhari who is buried there.
Now where is the question of Breast show up.
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