May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
Comments
when a human being brutally killed, people are talking based on religion...... shame on you guys...... see his face.... it is the height of the cruelty... may his soul rest in peace
ARUN KUMAR
DUBAI
Idiot YOGESH, don't just say what ever you get into your mind, I work for RSS & MRM, You should know the fact that Ismail nelyamajalu used to visit tirupathi lord balaji for darshan with his family once or twice a year, he also used to conduct jathara(festival) at a temple in sullia, DK, every year. He was a very kind human being more than a muslim & a politician.
A very good husband, father, brother and a friend, I personally know him since 2013.
Please know the facts before you bark.
Naren, you did not explain what is 72.....you are just making bow, bow,..... you are free to take action against any one making hate comments .....
Dear mr SK ,mr true Indian ...police commissioner alla even DIG bekadru complaint kodi ...mr viren ,bopanna and yogesh and including me have the right to comment ..its not a social media like Facebook and twitter to lodge complain ...this is strictly controlled by admin ......cyber cell will also check anti Hindu comments too ..do u think we will keep quiet ...? We also know laws ...how we can sit when our patriotic organisation like sangh is mocked ...so better mind ur business ...better u talk to CD ...being a responsible media they are responsible for posting news which don't instigate ...but they are not doing ....
Naren, singapore ..what is this figure of 72 ... can you explain further ????
True Indian, Mangalore...it is better to report such matters with mangalore police commissioner,Mr chandrashekar....
Frustrated Brothers Naren And Viren.Papa pandu.Day is not far to pay for all your Comments.In sha allah.We give damn to all your Comments.Carry On.
Papa athmakke shaanthi sigali ..mele 72 virgins sigali .........yelli faizhal Bhai kaanistha illa .....banree \ innu illari rajiwoon antha helree \""
Coastal Digest please do not entertain Brother Viren's Such Comment which disturbs the readers or else we will have to complain against him with the Cyber cell.Please take this message seriously.
Death is not a disaster simply a passing from this world onto the next. It should make us reflect and ponder about the purpose of the life and what will become of us after death. Innah ilahi wa inna ilaihi rajihoon Deep condolence insha Allah grant him forgiveness and higher in heavens. Ameen
I have conducted a survey of Friday murders in coastal Karnataka. Especially immediately after or before Muslims special prayers. 99% of such murders are committed by Muslims only.
So Yogesh is making a confession that BJP is behind this murder ?
Shocking incident, he was really a prominent leader of congress. anyways rest in peace.
May his soul rest in peace
whoever made this brutal crime must be punish them in the like same. seriously a inhuman act.
How people can b so cruel? Y can't we lead our four days of life happily. Inna lillahi wa inna ilayhi rajioon.
Innalillahi va inna ilayhi rajivoon
Innalillah
Inna lillahi wa inna elaihi rajiwoon.
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