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May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.

According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.

"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.

They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.

Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.

"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.

"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.

In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.

"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.

The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.

These children were then confirmed to have COVID-19.

While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.

Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.

According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.

"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.

Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.

While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.

However, he cautioned that more research is needed to confirm their findings.

"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.

Bengaluru, Jul 5: In the midst of the Covid-19 pandemic and the fear of layoffs lurking everywhere, the state government is holding a first-of-its-kind virtual job fair on July 10, to help people find jobs commensurate with their skill sets.

Co-ordinated by the Karnataka Skill Development Corporation (KSDC), the job fair will see participation of more than 40 companies for about 6,000 job openings.

The government will connect companies with job seekers who have registered on the recently-launched Skill Connect portal or on the Kaushalya Karnataka’s portal for migrant workers from the state who have returned home.

A candidate can either directly apply to a company, or await the portal to match their skills with available jobs. There is also a self-evaluation section on the website which will suggest whether a candidate needs to further skill oneself or whether they are eligible for jobs with their current set of skills. 

Firms such as Life Insurance Corporation, Barbeque Nation and Arvind Mills are among the participants.

Udupi, Jul 18: Noted multi-lingual scholar Dr Uliyar Padmanabha Upadhyaya passed away last night at a private hospital in Manipal. The 88-year-old was survived by a son and a daughter.

His wife Susheela Uadhyaya, who was also a multi-lingual scholar, had passed away in January 2014 at the age of 77. The duo had compiled the six-volume Tulu Lexicon. Its first volume was published in 1988 and the last volume in 1997.

Son of Sitaram Upadhyaya, who was a scholar in the court of the Raja of Travancore, Dr Padmanabha was born on April 10, 1932 at Uliyar in Majur Village near Kaup in Udupi district. 

The Upadhyaya couple had conducted serious research work in linguistics and folk culture and produced a number of books-some of them jointly, some individually and some in collaboration with others. 

Dr Padmanabha had acquired three Master of Arts degrees in Sanskrit, Kannada and Linguistics from Madras, Kerala and Pune Universities, Vidwan in Hindi and PhD in Linguistics from the Pune University for his thesis titled “A Comparative Study of Kannada Dialects”.

He was a visiting Professor at the Universities of London and Paris. He knew Hindi, Kannada, Tulu, Malayalam, Tamil, English, French and Olof, the language of Senegal in Africa.

His works include Nanjanagudu Kannada (Vokkaliga Dialect), Coorg Kannada, Kuruba - A Dravidian Language, Kannada - A Phonetic Language, Malayalam Language and Literature (with Ms. Susheela), Effect of Bilingualism on Bidar Kannada, Coimbatore Tamil, Kannada as Spoken by Different Population Groups in Mysore City, Dravidian and Negro African: Ethno Linguistic Study (with Ms. Susheela), Conversational Kannada, Coastal Karnataka and Bhuta Worship: Aspects of a Ritualistic Theatre (with Ms. Susheela).

Also Read: Eminent linguist Dr Susheela P Upadhyaya no more