Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.
However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.
New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.
The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.
It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.
"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.
As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.
"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.
"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.
To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.
At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.
Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.
In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.
They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.
Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.
The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.
Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.
Comments
He died of a powder, which was scheduled to end his rowdy there anything special that he did,
Finally RSS got the sponsors for their trousers.
Chaddi to Pants journey
Whoo!!! chaddis have become Panties now!!!
He is a victim...it could be a dirty political game. BJP-RSS finds a good guy in their own association & plots a plan against muslims by killing them. This is well known. But Allah is the best planner. None in the universe surpass him. Allahu Akbar
Dear Chinnan , we condemn innocent's killings ....but these (RSS) are traitors who plot to kill INDIAN Citizens.....and hoisting Pakistani flag in Sindhagi
Muslims never betrayed INDIA .....these are you who traited our country
Quran Says 5:32 Whoever kills a person (unjustly)it is as though he has killed all Mankind. And whoever saves a life it is as though he had saved all Mankind.
Dont judge islam by seeing people rather Islam is totally opposite to what you see.
@ Naresh kotian. Your barking statement neither bring any solution to calm the situation nor influence the people of any faith, unless they are sick minded. I have been reading your sick comments every time, and I'm sorry to say that you are a uncivilized
Some of the morons like Kotians in this forum are suffering from inferior complex
They are jealous about Muslims. And I still wonder why Indian Muslims are associated with the neighbour country when there is no connection .
Why can't u associate us with countries like Saudi Arabia UAE etc
This reflects their cheap mentality and intolerance, which is taught in their chaddi Shaka's
And why surgical within...,if Allah wills a tsunami like natural disaster can wipe out entire humanity without differntiating Hindus mulsim Christians
So stop this hatred towards other communities
And look at the deceased. In which angle he looks like a RSS worker...bcos he looks like a goon.This murder could be for Girl, real estate or drug
Why drag muslims to it , Think why he is killed , muslims do not celebrate death of any person.. If deceased is having criminal back ground , it is a lesson to other criminals , same may face same end...
bros.... why roam with hate minds... spread happiness , accept reality...
Naina, Vijaya,
Please do not come to your own conclusion....let the law take its course of action.....don't count the chicken before hatch....
Its very bad!
RIP ....there is no safety for Hindus in rashtra drohi community controlled congress ..they hacked Prashanth ,charan kuttappa and Raju ....now rudresh....jai Sri ram ....jihadis will certainly have to face repercussions ...they were upset with surgical strikes on their co brothers in pak ...now its high time surgical strikes needed within ....jai sangh parivar ....
@laila; Stop dragging, muslims into ur dirty hindusht politics
Vote bank politics at its best. An RSS worker killed nothing happens! When a Muslim or a Christian is killed (not a good thing either) it is award wapasi time. Sick Congress and Leftists!
No one deserves to be killed in a civilised society.
These type of murders and lynchings etc always happen, just before any elections. These are happening right from Nehru's period. He murdered Shyama Prasad Mukherjee, Rafiq Ahmed Kidwai etc. few more BJP and RSS workers will be murdered by Congress
RSS ? what does it stand for? Rahul-Sonia Slave ?
If a RSS worker is killed it is not a considerable offence because they are fundamentalists. If the same thing happened to others it means atrocities, anti secular, anti national, terrorist activity. When we will get up and live in the environment of reality.
@shiva, If people start killing people of one particular community for insulting girls then almost 90% of them will vanish.
I hate RSS and their Bhakts but killing any person in such a way should be condemned...... If people started killing Bhakts for insulting girls then more than 70% of Bhakts will vanish.
Hack the culprits back in a same way. hindus will not tolerate any oppression either..
If u live by sword, u die by sword
The Cong govt has no answer to give to the people over its failure to protect innocent hindus.
This should not have happened. Very sad. May Almighty Allah give courage and strength to the bereaved family members, relatives and friends to bear this irreparable loss.
Weak policing all over the country are bolstering the criminals to beat, kill, maime each other. Terrible. Strictest action needed.
Hindu murdered,all of u have no problem
But if a muslim/ Christian was murdered,u call it as fascism,terrorism,brutality,...olakkeede moody
What a ****** country
How We Hindus live here
i remember
Kalburgi
Panasare
Dabolkhar...
PARA NARI rudresh is a GOONDA. CPI(M) fools people in the name of secularism. For them secularism is being anti Hindu. They dare dont criticise Islam and its traditions but take pride in talking ill of Hindu traditions and Hinduism.
Lives of Hindus are in dangers under Siddu govt :(
It's Muslim groups who is doing to bjp
It seems rationalists are having a bad time in the sub-continent for the years. Shame really!
So sorry to hear that..
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