May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
Comments
If RSS and other chillar saffron pillas are banned....then all Muslim based parties will surely back off....try it
..India will be a Better place to live......
if u say to ban SDPI and PFI wht abt the killers who killed more thn 1000's of Muslim & Dalits in india who will ban those who killed this muslims & dalits they are nationlist this RSS VHP ABVP Sangi shld b banned first in india if you ban this guys thn india will b peace country y u all involving kerala in this in kerala they kill for political reason @mohan and @nirmal u mean to ban all the parties in kerala and in india thn only RSS will rule the country no it will never happen everyone hve rights in india dont point others b4 pointing others look into you wht you guys are upto thn point others for ban or anything wht RSS do notice tht firts insted saying to other parites
First RSS should be banned. Then automatically there wont be any problem, coz the root cause of all the hatred is from this organization.
Also Ban Praveen Poojary killers & thier organization like Bajarang dal , VHP , HJV and Gow rakshak sangs ! !
How about RSS involved in various terrorist activity....I am not a member of both parties....but who are these tapaories to ban....
Same way why don't they ask central govt to ban gang, which is involved in killing Udupi Praveen Poojary?
A new TWIST to hide the real CULPRITS who were caught few days back... We all know cheddis evil agenda ... We dont trust them anymore....
How many times you asked centre When RSS members were hacked to death in Kerala . multiple times in a year ........? that means LDF UDF Congress......CPM and other parties should be banned for killing RSS members ?
If it was possible . then long back would have done .......this is GOD's World .....No evil can claim as its own.......Wa jaa'a haqq wa zahakal bathil ...........Falsehood should persih ...as it is bound to perish .......
and remember RSS is not patriotic not Hindu Organization..........and who are you to ask centre ......BJP elected not to control but to maintain a country
cpm and BJP are in open war in kerala and killing each other , never find any wrong on them ... any govt ruled in India since 70 years never find any guilty on RSS , where as most of the reports pointed its direct hands and some times its ideology behind it ...
central govt may hurriedly take action , if anybody approach action against PFI , as they effortlessly working to ban ZAkir naik and his org.. and keen to ban triple talaq.
Ban Also the Killers of
Ghandhi
Dabolkar
Panesar
Karkera
Akhlaq
hahahahahaha, what are these guys upto, they kill their own members and point out other organization.
when go rakshak killed the bjp worker, why did you keep quiet, did u ask govt to ban go rakshak.
This clearly says their intention is communal hatred.
America enlisted RSS in one of the Biggest Terrorist organization. Assam123.com.
The agenda of banning PFI and SDPI already there since RSS is running the central govt. But its hard nuts crack.
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