May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
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ramadam went came again again went .He is not seen like you .Pls do not bring religion in all things
hello bhai super pls send u r no. all the best
Rana krishna 10 Cross heghe nagar
hi zaid bro welcome to bollywood industry
May almighty Allah guide all Muslim ummah to the straight path. Ameen.
Holy month of Ramadan, film releasing, so sad!
Br. Zaid, may Allah guide you to be a good and religious muslim. Whatever your physical apperance is, from Allah, it's not of your's. It is like a floating buble on the surface of stream of water. It won't appear for a long, so like we, the human beings. After that, you think of your physical appreance. In this holy month of Ramadan each & every Muslim maximum trying to obey Allah & get pleased by Him. Don't think that the life what we are enjoying is the real life, but our real life really means from the moment of our death. So, fear Allah and refrain from your present decission and put all your efforts to be a good practical muslim and there by teach your dad & whole family about \deen e islam. May Allah bless you forever to make use of your tallents to study, practise & preach the correct deen in its origial shape. By your Brother in Islam. Yaa ayyu alladeena aamanu koo amfusikum va ahleekum naara, this ayath of quran reminds every muslim to safe guard them selves and fellow muslims from the hell fire."
Not necessary all Khans should be a super hit. Look at those Khans like ZAHID Khan, Imran Khan, Ayyub Khan, Kamal Khan and so on and so forth. They are not been seen now.
Good news in Ramadan. The Khan rule is all set to begin in Kannada film industry (sandalwood) like Bollywood. Congratulations to Zaid Khan the future super star of south India. Good that you r starting your film career in Ramadan. that too in last 10 days of Ramadan. wah kya kamal ki batth. masha allah. swarga guarantee...
all khans are ganapathi khans.. severel years back mr zameer ahmed had given ganapati idol to mr kumarswamy as his birth day gift.. that mean this khan also is a devoti of ganapati like bolly wood khan sharuk and salman keep it up
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