Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.
However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.
New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.
The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.
It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.
"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.
As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.
"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.
"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.
To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.
At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.
Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.
In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.
They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.
Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.
The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.
Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.
Comments
practice madidre full madabeku ...sumne shoki ge haakondu barodalla ...let her go and teach in Islamic university or madrasa ...avra community nalli ondu school and college quality education kodalla ..so heegagi illi bandu ..build up bere ....as per Islam ...non Muslim men should not look at Muslim women ..this lady has not covered face and hands ..high time hijab tax must be put .
Well done....
Good decision since she has trust on Creator... she is not going to die if she left this job... she may get better one...
Divine rule says it is better for the women to wear Modestly.. The women who use their god given intellect will recognize this blessing and follow it.... May ALLaH have mercy on them and protect them ... & May ALLAH guide those who are ignorant of this blessings.
Some of them without verifying the issue are ignorantly opposing it... It is for their benefit & protect oneself when the whole world is going god less... and living worst then animals now a days.
ALLAH is most merciful and most compassionate.. People should read the QURAN which is the manual for whole of mankind and a blessing for the LIFE ... Those who are missing it are really in DARKNESS of their LIFE ...
People heedlessly living their life and without proper knowledge, they come to conclusion & attack those who follow the divine rule.
For ME God's law is the best and it will protect me from the evil eyes of todays world..
Thank u True indian. U opened my eyes.
Ur absolutely correct. I prefer my sister or mom to wear hijab and cover her body fully. Instead of wearing mini skirts.
@bopanna
That means u don't respect Sita mata. Can't u see hijab on all sita matas pictures and idols
SISTER a great salute to you as you follow islam and imaan . with the heart
Even muslims respect Sita mata. Because on her all the pictures and idols. We can see her head is covered with hijab.
I think all women should wear hijab. It protects from evil eyes.
Keep your religion at home .... dont show off to hindu students
if u see Sita mata's Photo. She wears Hijab in all her Pictures.
Will they remove Sita Matas Hijab on all her idols?
O People of INDIA ....remember one thing ...many civilization has brith and death according it dealing with GOD and his rules.....so never late just repent and be good to every one . or else Aad and thamud will be reminded on this earth .
forget INDIA ....even country like USSR were destroyed by GOD using small groupf of unarmed and unskilled fighters from backward country ....so becarefull do not cros the border of aggression ....
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