May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
Comments
Some cases people do not know how pakistan flag looks and Islamic flag ... just see green colour and assume pakistan flag... last time SRS member hosted pakistan flag not islamic one..
pakistani flag nowhere near to islamic flag. Green is not islamic flag
What a comment from Master Blaster Ganeshanna are you Citizen of Hindustan? A flag issue you are sending a Indian Citizen to pakistan is it Fair.. YOU biggest buffoon's doing to our Great Hindustan !!!!!!
What you thought about Hindustan, we are proud ourselves like Peanut we do not care Anna, Gangasara makes things very difficult!!!!!!
Jai Hoo Hindustan.
By the way where we can send this Rama Sene for hoisting pakistan flag? Please suggest a country @ Truth Mangalore, Ganesh, Unknown.. Please suggest them a country too,
Many readers here are suggest to arrest the youth and kick him out to Pakistan for hoisting Pak flag (not yet confirmed). However, they are hiding to tell the truth about hoisting Pak flag by SRS terrorists. Instead of asking the culprits to punish, they had supported these goondas. This was done only to blame minorities. In the particular case also i doubt that it was fabricated by sangh parivar. This should be investigated and the person should be punished in case he really hoisted pak flag. However, please make is clear that he is not mentally sick.
enquire about the person who is behind and put him behind the bars....what about the pakistani flag hosted by sri rama sene member before ?????????????? where we need to send him.
Add new comment