Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.
However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.
New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.
The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.
It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.
"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.
As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.
"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.
"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.
To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.
At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.
Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.
In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.
They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.
Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.
The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.
Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.
Comments
who knows with immense pressure from policticans he might have been framed ..becoz ruling party needs one particular community votes and we know how murders of prashanth poojari and vaman poojari ( witness in murder ) got closed .vaman poojaris death shown as suicide .prashanth poojari murder cases all accused are getting acquitted .one jihadi who shouted islamic war cry while butchering our prashant poojari was standing next to abhaya chandra jain ... so conspiracy theory cannot be ruled out ... ankit is just accused and he is not proven guilty , so let our court decide who is culprit ... we dont talk in rubbish language like hang him , shoot him ... as we are not living in third rated countries , which asks proof from males if rape has hapened ...such a pathetic rules ...long live sangh parivar ... jaio sri ram
Narianna....are you not aware that the bloody goon has admitted his criminal deeds... Are u still in the influence of snake food ??? ....
If he comes out within 10 days, I will be not surprised, since we know the DNA of Indians .... as it happened in the case of Sadvi and Akshamdam cases....
I dont think he has stabbed ..if proved , let him be punished for murder ... but certainly not for silly silly cases ...
comment #16 , first ninna community members ge lecture kodu mama ... no need to advise billawa leaders ... third rated kelasa maaadtha irodu nimma jana maarre ... Mr Kazi , we are not living in third rated country to hang anyone without trial and he has not done any major mistake ... anyways he will come out within 10 days ...love to see many one particular community guys using hindu names and posting their frustration .:) hahaha ...
before punishing this culprit, find which VHP criminal is behind this idiot fellow and put him in the jail forever
These Billava boys are brain washed by RSS leaders. Why can't they brain wash their own children for such criminal act? No they will send their children to abroad for higher studies and for job.
Billava leaders must open their mind and guide their youngsters the real motto of these RSS leaders and keep them away from their bhakthi. etc.
baddy maga, i am waiting for him to get in case like this, he s flying all the time in our colony, police should break his leg again he should not enter our place.
Viren, right is right and wrong is wrong....where is the proof for your allegation against minorities....totally rubbish.....This criminal has been thought to do this by Sanghis to promote communal disharmony around.....
Good job police, specially the mosque for installing CCTV camera, otherwise this criminal would have went scott free. Give him harshest punishment so that others should learn good lesson from it....
Viren ..........No killing justfied .....as far as Nationalism concern no one need your Help...thay all know who you are and your dirty RSS and its wings....so keep your Brahmanism with you at home ....we all know who killed RTI Activists that too being a HINDU....OK ...adella OK neevu ee deshadalli dwesha YAKE ...saaka ?
Elli Nyaya illavo allide ....karya...
send him out of india, hang him to death,,,very dangerous people....
lets pray for his family, god bless u all.
this is a serious issue, should consider him as a main suspect of all the crime and should investigate properly all the goons should be caught and punished properly, my big suggestion is to cut the legs of these type of goons and let them sit on streets for begging,
Very Sad news rickshaw driver, \let his soul rest in peace\" but killing in Hindustan, stone pelting in Hindustan all these doing are really condemnable, but this Criminal does not look like Poojary Family definitely I belong too but his Nature his body language looks like \"Cross Breed\" you readers must have understood that means must Illegal!!!!!!! so you Understand our Local language says for that type of Goons, he never ever can become a good Human, if you punish or put in Jail whatever you do Tail of \"DOG\" can never become straight
Jai hoo Modianna"
guilty must be punished.
Every crime is condemnable. but, we all know that you are a nationalist. If compared to the crime of those who back stab our motherland what u did is nothing.
totally Brain washed by the RSS goons.
lets kill this dog in street by stone.
Should be put on Lie detector, to get the details of his masters / brain washers / supporters .... Afterwords should be hanged in a public place .... as a lesson for the other goons of the coastal districts ...
hang him to death, these type of creatures are creating trouble to the society.
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