After Ahmed Patel’s victory D K Shivakumar emerges as a Cong hero

Bengaluru, June 7: Promising Kannada actor Chiranjeevi Sarja died of heart attack in Bengaluru on Sunday. He was 39. 

The actor complained of severe chest pain and respiratory problems on Saturday. He was immediately rushed to Sagar hospital in Jayanagar, according to sources.

It is said that he suffered heart attack. Doctors attempted to revive him, but the efforts failed.

Chiranjeevi Sarja, the relative of mutlilingual South Indian actor, Arjun Sarja, had married Meghana Raj, the daughter of Prameela Joshai and Sundar Raj in 2018. He acted in 22 films. 

His throat swab sample have been sent for testing, added the sources.

He had started his career with Vayuputra in 2009. Shivarjuna, which was his last film, had released days before lockdown was imposed.

In October 2017, he was engaged to actress Meghana Raj. They married on 2 May 2018.

Beijing/Zurich, Mar 4: China has approved the use of Swiss drugmaker Roche's anti-inflammation drug Actemra for patients who develop severe complications from the coronavirus as it urgently hunts for new ways to combat the deadly infection that is spreading worldwide.

China is hoping that some older drugs could stop severe cytokine release syndrome (CRS), or cytokine storms, an overreaction of the immune system which is considered a major factor behind catastrophic organ failure and death in some coronavirus patients.

Actemra, a biologic drug approved in 2010 in the United States for rheumatoid arthritis (RA), inhibits high Interleukin 6 (IL-6) protein levels that drive some inflammatory diseases.

China's National Health Commission said in treatment guidelines published online on Wednesday that Actemra can now be used to treat coronavirus patients with serious lung damage and high IL-6 levels.

Separately, researchers in the country are testing Actemra, known generically as tocilizumab, in a clinical trial expected to include 188 coronavirus patients and running until May 10.

Roche, which donated 14 million yuan ($2.02 million) worth of Actemra during February, said the trial was initiated independently by a third party with the aim of exploring the efficacy and safety of the drug in coronavirus patients with CRS.

It added that there was currently no published clinical trial data on the drug's safety or efficacy against the virus.

More than 3,000 people have died and 93,000 have been infected by the novel coronavirus thought to have originated in Wuhan, China, before spreading to around 90 countries including the United States, Italy, Switzerland, France and Germany.

The Swiss company, for which China is its No. 2 market behind the United States, also makes diagnostic gear to detect the coronavirus.

Since Actemra's approval a decade ago, it has become a go-to drug against other inflammatory conditions, including cytokine storms in cancer patients receiving cell therapies from Novartis and Gilead Sciences.

In 2012 it helped save the life of a young U.S. girl, the first child to be treated for leukaemia with Novatis' Kymriah, from a post-treatment rush of IL-6.

Priced at between $20-30,000 annually for RA according to SSR Health, Roche's medicine is also used for rare juvenile arthritis and giant cell arteritis, or inflammation of the blood vessels.

Udupi, May 18: G Jagadeesh, Deputy Commissioner of Udupi today warned that criminal cases would be filed, if people under quarantine roam around, as they put the lives of others in risk, by coming out.

He said: "There are more than 6,000 people under quarantine in hotels, hostels, schools etc in different parts of the district. They include those who returned from other countries and other states.”

“We have allowed them to return to the district. Now I am receiving complaints that many of them are violating quarantine guidelines and venturing out. This is unacceptable.”

“As it is a risk to the whole society, severe action will be taken against the neglect and apathy of the persons under quarantine,” he said.