May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
Comments
With all due respects, to all our brothern Hindus,
One thing sure, series of babas because who are not allowed to marry are indulged in rape, adultary cases.
Babas who called Godman became criminals.
Hindus should not be so stupid to allow these babas to commit more crime and spoil the name of Hinduism.
If you dont allow them, you are risking your daughters in a very dangererous state. May God really help.
why are the hording in hindi, do this people not respect kannada and kannadigas?
@Hari... In that matter, Kerala media did well. They didnt give much importance to Amit Shah's visit. Kerala media covered actor Dileep issue at that time. But cunning Shah brought national pro cheddi media there for his programmes
They are coming for spreading hatred and communal thinking.. should avoid them and should not attend thier programmes. Even media should not cover thier arrival with much importance
LOL... Yogi and Shah from the state, which has no sufficient toilets for people and they are talking about development... Greeeeaaaaat
Communal Yogi and shahspoiled Mangaluru' sacredness
I heard speech of Yogi, while he visited Kerala. Fool Yogi told Kerala govt to learn hospital treatments and life care from UP hospitals... See the irony - Yogi, who is the reason for death of 61 children ask to learn from hospital things to Kerala govt, where health care sector having no. 1 position among Indian states
Mangaluru was sacred place just before your arrival. You spoiled that with blood stains of 61 children and many raped women
See the face of swamis, really public are idiots
Sacred land with feku babas... Yogi better concentrate on your UP land. First try to develop your UP then give advice to others. Our manglore is developing and we do not need your advise. Try to correct law and order in your state. I wonder why you became CM.. Instead of that you could have become a sadhu or pandith. This will be good and suitable for you. Also try to learn the meaning of DEVELOPMENT!!!!
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